DEFICIENCY OF MYELOID PHD PROTEINS AGGRAVATES ATHEROGENESIS VIA MACROPHAGE APOPTOSIS AND PARACRINE FIBROTIC SIGNALING: Atherogenic results of myeloid PHD knockdown

Goals: Atherosclerotic plaque hypoxia is detrimental for macrophage operate. Prolyl hydroxylases (PHDs) provoke mobile hypoxic responses, presumably influencing macrophage operate in plaque hypoxia. Thus, we aimed to elucidate the position of myeloid PHDs in atherosclerosis.

Strategies & outcomes: Myeloid particular PHD knockout (PHDko) mice had been obtained through bone marrow transplantation (PHD1ko, PHD3ko) or conditional knockdown by means of lysozyme M-driven Cre recombinase (PHD2cko). Mice had been fed excessive ldl cholesterol eating regimen for 6-12 weeks to induce atherosclerosis. Aortic root plaque measurement was considerably augmented 2.6-fold in PHD2cko, and 1.4-fold in PHD3ko in comparison with controls, however was unchanged in PHD1ko mice. Macrophage apoptosis was promoted in PHD2cko and PHD3ko mice in vitro and in vivo, through the HIF1α/BNIP3 axis. Bulk and single cell RNA knowledge of PHD2cko bone-marrow-derived macrophages (BMDM) and plaque macrophages, respectively, confirmed enhanced HIF1α/BNIP3 signaling, which was validated in vitro by siRNA silencing. Human plaque BNIP3 mRNA was positively related to plaque necrotic core measurement, suggesting comparable pro-apoptotic results in human.

Additional, PHD2cko plaques displayed enhanced fibrosis, whereas macrophage collagen breakdown by matrix metalloproteinases, collagen manufacturing and proliferation had been unaltered. As an alternative, PHD2cko BMDMs enhanced fibroblast collagen secretion in a paracrine method. In silico evaluation of macrophage-fibroblast communication predicted SPP1 (osteopontin) signaling as regulator, which was corroborated by enhanced plaque SPP1 protein in vivo. Elevated SPP1 mRNA expression upon PHD2cko was preferentially noticed in foamy plaque macrophages expressing “triggering receptor expressed on myeloid cells-2” (TREM2hi) evidenced by single-cell RNA, however not in neutrophils. This confirmed enhanced fibrotic signaling by PHD2cko macrophages to fibroblasts, in vitro in addition to in vivo.

Conclusion: Myeloid PHD2cko and PHD3ko enhanced atherosclerotic plaque progress and macrophage apoptosis, whereas PHD2cko macrophages additional activated collagen secretion by fibroblasts in vitro, possible through paracrine SPP1 signaling by means of TREM2hi macrophages.

Translational outlook: This research exhibits that myeloid PHD isoforms PHD2 and PHD3 worsen plaque traits and phenotype, corresponding to plaque measurement, macrophage accumulation, apoptosis, and collagen accumulation in mice. We present each direct results on macrophages and paracrine results of macrophage PHD2 loss on vessel wall fibroblast populations. Broad spectrum-PHD inhibitors, e.g. Roxadustat, are presently being prescribed to power kidney illness sufferers, who’re already in danger for heart problems. When contemplating this research and the pro-fibrotic and pro-apoptotic results we report, broad PHD inhibition might due to this fact be sub-optimal and extra focused PHD inhibition of PHD1 must be thought of.

The results of various temperatures of post-exercise protein-containing drink on gastric motility and power consumption in wholesome younger males 

The current research examined the consequences of various temperatures of protein-containing drink after train on subsequent gastric motility and power consumption in wholesome younger males. Twelve wholesome younger males accomplished three, one-day trials in a random order. In all trials, the topics ran on a treadmill for 30 min at 80% of most coronary heart fee. In train + chilly drink (2 °C) and train + sizzling drink (60 °C) trials, the topics consumed 300 mL of protein-containing drink (0.34 MJ) at 2 °C or 60 °C over a 5-min interval after train. Within the train (i.e., no preload) trial, the topics sat on a chair for five min after train. Then, the topics sat on a chair for 30 min to measure their gastric motility with an ultrasound imaging system in all trials.

Thereafter, the topics consumed a take a look at meal till they felt comfortably full. Vitality consumption within the train + sizzling drink trial was 14 % and 15 % greater than the train (P=0.046, 95% CI: 4.010-482.538) trial and train + chilly drink (P=0.001, 95% CI: 160.089-517.111) trial, respectively. The frequency of the gastric contractions within the train + sizzling drink trial was greater than the train (P=0.023) trial and train + chilly drink (P=0.007) trial. The overall frequency of gastric contractions was positively associated to power consumption (r=0.386, P=0.022). These findings reveal that consuming protein-containing drink after train at 60 °C will increase power consumption and that this improve could also be associated to the modulation of the gastric motility.

Anti-Total Goat Milk Proteins
4042-AF	Cygnus Technologies	1 mg	EUR 1913
Product category: Antibodies
Description: Anti-Total Goat Milk Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Total Goat Milk Proteins
4042-PA	Cygnus Technologies	1 ml	EUR 488
Product category: Antibodies
Description: Anti-Total Goat Milk Proteins by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Sample Diluent
F243A	Cygnus Technologies	1000 ml	EUR 565
Product category: Buffer solution
Description: Goat Milk Proteins Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Sample Diluent
F243A-100	Cygnus Technologies	100 ml	EUR 257
Product category: Buffer solution
Description: Goat Milk Proteins Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Sample Diluent
F243A-500	Cygnus Technologies	500 ml	EUR 411
Product category: Buffer solution
Description: Goat Milk Proteins Sample Diluent by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Antigen Concentrate
F243H	Cygnus Technologies	100 ul	EUR 411
Product category: Quality control/standard for molecular biology applications
Description: Goat Milk Proteins Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

Goat Milk Proteins Control Antigen
F247	Cygnus Technologies	50 ul	EUR 257
Product category: Quality control/standard for molecular biology applications
Description: Goat Milk Proteins Control Antigen by Cygnus Technologies is available in Europe via Gentaur.

Total Goat Milk Proteins ELISA kit
F240	Cygnus Technologies	1 kit (96 wells plate)	EUR 1080
Product category: Enzyme linked immunosorbent assay (ELISA) kit.
Description: Total Goat Milk Proteins ELISA kit by Cygnus Technologies is available in Europe via Gentaur.

Total Goat Milk Proteins WB kit
F245	Cygnus Technologies	1 kit (application dependant amount of reactions)	EUR 836
Product category: Premade blotting kit
Description: Total Goat Milk Proteins WB kit by Cygnus Technologies is available in Europe via Gentaur.

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN	ImmunoStep	50 µg	EUR 349

Anti-milk fat globulin antibody
STJ16100177	St John's Laboratory	100 µg	EUR 406

Human milk specific allergen antibody(IgE) ELISA Kit
CSB-E15859h-24T	Cusabio	1 plate of 24 wells	EUR 165
Sample volume: 50-100ul Detection wavelength: 450nm Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human milk specific allergen antibody (IgE) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human milk specific allergen antibody(IgE) ELISA Kit
1-CSB-E15859h	Cusabio	EUR 804.00 EUR 5099.00 EUR 2704.00	1 plate of 96 wells 10 plates of 96 wells each 5 plates of 96 wells each
Sample volume: 50-100ul Detection wavelength: 450nm Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human milk specific allergen antibody(IgE) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Anti-Goat Milk Proteins:HRP Conjugate
F241	Cygnus Technologies	12 ml	EUR 488
Product category: Antibodies
Description: Anti-Goat Milk Proteins:HRP Conjugate by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04	Cygnus Technologies	1 ml	EUR 334
Product category: Antibodies
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04-AF	Cygnus Technologies	1 mg	EUR 1913
Product category: Antibodies
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04-PA	Cygnus Technologies	1 ml	EUR 488
Product category: Antibodies
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Anti-Bovine Plasma Proteins
BPP04AF-HRP	Cygnus Technologies	100 ul	EUR 989
Product category: Antibodies
Description: Anti-Bovine Plasma Proteins by Cygnus Technologies is available in Europe via Gentaur.

Skim Milk
abx082021-100g	Abbexa	100 g	EUR 217
Shipped within 5-10 working days.

anti-Human Milk Fat Globule 1
YF-PA13135	Abfrontier	50 ug	EUR 363
Description: Mouse polyclonal to Human Milk Fat Globule 1

anti-Human Milk Fat Globule 1
YF-PA13136	Abfrontier	100 ul	EUR 403
Description: Rabbit polyclonal to Human Milk Fat Globule 1

anti-Human Milk Fat Globule 1
YF-PA13137	Abfrontier	100 ug	EUR 403
Description: Rabbit polyclonal to Human Milk Fat Globule 1

anti-Human Milk Fat Globule 1
YF-PA24148	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to Human Milk Fat Globule 1

Anti-Human Milk Fat Globule 1/MFGE8 Antibody
PA1945	BosterBio	100ug/vial	EUR 334

Polyclonal Goat anti-GST α-form
GST-ANTI-1	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2	Detroit R&D	50 uL	EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3	Detroit R&D	50 uL	EUR 280

Lys proteins Antibody
abx219526-100ug	Abbexa	100 ug	EUR 439
Shipped within 5-10 working days.

Lys proteins Antibody
ABD2705	Lifescience Market	100 ug	EUR 438

Lys proteins Antibody
DF2705	Affbiotech	200ul	EUR 304
Description: Lys proteins antibody detects endogenous levels of total Lys proteins.

anti- ATF2-Specific antibody
FNab00661	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: activating transcription factor 2 Uniprot ID: P15336 Research Area: Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology
Description: Antibody raised against ATF2-Specific

anti- ATP1A1-Specific antibody
FNab00692	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:1000-1:4000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: ATPase, Na+/K+ transporting, alpha 1 polypeptide Uniprot ID: P05023 Research Area: Neuroscience, Metabolism
Description: Antibody raised against ATP1A1-Specific

anti- ATP1A2-Specific antibody
FNab00694	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: ATPase, Na+/K+ transporting, alpha 2(+) polypeptide Uniprot ID: P50993 Gene ID: 477 Research Area: Neuroscience, Metabolism
Description: Antibody raised against ATP1A2-Specific

anti- ATP5G2-Specific antibody
FNab00708	FN Test	100µg	EUR 505.25
Immunogen: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2(subunit 9) Uniprot ID: Q06055 Research Area: Metabolism
Description: Antibody raised against ATP5G2-Specific

anti- BAG1S-specific antibody
FNab00788	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: BCL2-associated athanogene Uniprot ID: Q99933 Gene ID: 573 Research Area: Cardiovascular, Signal Transduction
Description: Antibody raised against BAG1S-specific

anti- BAI2-Specific antibody
FNab00791	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: brain-specific angiogenesis inhibitor 2 Uniprot ID: O60241 Research Area: Signal Transduction, Developmental biology
Description: Antibody raised against BAI2-Specific

anti- BAI3-Specific antibody
FNab00792	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 Immunogen: brain-specific angiogenesis inhibitor 3 Uniprot ID: O60242 Research Area: Signal Transduction, Developmental biology
Description: Antibody raised against BAI3-Specific

anti- Barkor-Specific antibody
FNab00806	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IP: 1:500-1:1000 IF: 1:10-1:100 Immunogen: KIAA0831 Uniprot ID: Q6ZNE5 Gene ID: 22863 Research Area: Cancer, Immunology
Description: Antibody raised against Barkor-Specific

anti- BLOC1S1-Specific antibody
FNab00909	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: biogenesis of lysosomal organelles complex-1, subunit 1 Uniprot ID: P78537 Research Area: Cardiovascular, Metabolism
Description: Antibody raised against BLOC1S1-Specific

anti- BRN2-Specific antibody
FNab00963	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: POU class 3 homeobox 2 Uniprot ID: P20265 Research Area: Neuroscience, Epigenetics, Metabolism, Developmental biology
Description: Antibody raised against BRN2-Specific

anti- CAPG-Specific antibody
FNab01249	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: capping protein(actin filament), gelsolin-like Uniprot ID: P40121 Research Area: Signal Transduction, Immunology, epigenetics
Description: Antibody raised against CAPG-Specific

anti- Catalase-Specific antibody
FNab01302	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:1000-1:4000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: catalase Uniprot ID: P04040 Gene ID: 847 Research Area: Metabolism
Description: Antibody raised against Catalase-Specific

anti- CCKAR-specific antibody
FNab01377	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: cholecystokinin A receptor Uniprot ID: P32238 Gene ID: 886 Research Area: Neuroscience, Signal Transduction, Metabolism
Description: Antibody raised against CCKAR-specific

anti- CCKBR-specific antibody
FNab01378	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IF: 1:10-1:100 Immunogen: cholecystokinin B receptor Uniprot ID: P32239 Gene ID: 887 Research Area: Neuroscience, Signal Transduction, Metabolism
Description: Antibody raised against CCKBR-specific

anti- CCR2-specific antibody
FNab01390	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: chemokine(C-C motif) receptor 2 Uniprot ID: P41597 Research Area: Cardiovascular, cardiovascular, Cancer, Signal Transduction
Description: Antibody raised against CCR2-specific

anti- CCT6A-Specific antibody
FNab01401	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 Immunogen: chaperonin containing TCP1, subunit 6A(zeta 1) Uniprot ID: P40227 Research Area: Metabolism
Description: Antibody raised against CCT6A-Specific

anti- CDH10-specific antibody
FNab01546	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 Immunogen: cadherin 10, type 2(T2-cadherin) Uniprot ID: Q9Y6N8 Research Area: Immunology, Signal Transduction, Developmental biology
Description: Antibody raised against CDH10-specific

anti- CDK1-Specific antibody
FNab01552	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 IHC: 1:100-1:400 IF: 1:20-1:200 Immunogen: cell division cycle 2, G1 to S and G2 to M Uniprot ID: P06493 Research Area: Neuroscience, Metabolism, Immunology, Cell Division and Proliferation
Description: Antibody raised against CDK1-Specific

anti- CEACAM3-Specific antibody
FNab01578	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: carcinoembryonic antigen-related cell adhesion molecule 3 Uniprot ID: P40198 Research Area: Stem Cells, Immunology, Signal Transduction
Description: Antibody raised against CEACAM3-Specific

anti- CEP350-Specific antibody
FNab01603	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: centrosomal protein 350kDa Uniprot ID: Q5VT06 Gene ID: 9857 Research Area: Signal Transduction, Proliferation, Epigenetics
Description: Antibody raised against CEP350-Specific

anti- CES7-Specific antibody
FNab01618	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 IF: 1:20-1:200 Immunogen: carboxylesterase 7 Uniprot ID: Q6NT32 Research Area: Metabolism
Description: Antibody raised against CES7-Specific

anti- CHST13-Specific antibody
FNab01693	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IF: 1:10-1:100 IHC: 1:20-1:200 Immunogen: carbohydrate(chondroitin 4) sulfotransferase 13 Uniprot ID: Q8NET6 Research Area: Metabolism
Description: Antibody raised against CHST13-Specific

anti- CISD2-Specific antibody
FNab01719	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:2000-1:16000 IHC: 1:20-1:200 IF: 1:50-1:500 Immunogen: CDGSH iron sulfur domain 2 Uniprot ID: Q8N5K1 Research Area: Signal Transduction
Description: Antibody raised against CISD2-Specific

anti- CPNE9-Specific antibody
FNab01932	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 Immunogen: copine family member IX Uniprot ID: Q8IYJ1 Research Area: Metabolism
Description: Antibody raised against CPNE9-Specific

anti- CPT1B-specific antibody
FNab01944	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IHC: 1:50-1:500 IP: 1:500-1:1000 Immunogen: carnitine palmitoyltransferase 1B(muscle) Uniprot ID: Q92523 Research Area: Metabolism
Description: Antibody raised against CPT1B-specific

anti- CPT1C-specific antibody
FNab01946	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:50-1:500 IP: 1:500-1:1000 Immunogen: carnitine palmitoyltransferase 1C Uniprot ID: Q8TCG5 Research Area: Metabolism
Description: Antibody raised against CPT1C-specific

anti- CRLS1-Specific antibody
FNab01983	FN Test	100µg	EUR 548.75
Recommended dilution: IHC: 1:50-1:500 Immunogen: cardiolipin synthase 1 Uniprot ID: Q9UJA2 Research Area: Metabolism
Description: Antibody raised against CRLS1-Specific

anti- CST2-Specific antibody
FNab02033	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 Immunogen: cystatin SA Uniprot ID: P09228 Research Area: Metabolism
Description: Antibody raised against CST2-Specific

anti- CSTL1-Specific antibody
FNab02041	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: cystatin-like 1 Uniprot ID: Q9H114 Research Area: Metabolism
Description: Antibody raised against CSTL1-Specific

anti- CUL4A-Specific antibody
FNab02078	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:20-1:200 Immunogen: cullin 4A Uniprot ID: Q13619 Research Area: Metabolism
Description: Antibody raised against CUL4A-Specific

anti- CXCR3B-specific antibody
FNab02101	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:5000 Immunogen: chemokine(C-X-C motif) receptor 3 Uniprot ID: P49682 Research Area: Stem Cells, Immunology, Signal Transduction
Description: Antibody raised against CXCR3B-specific

anti- CXCR7-Specific antibody
FNab02107	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 IHC: 1:50-1:500 IP: 1:500-1:1000 Immunogen: chemokine(C-X-C motif) receptor 7 Uniprot ID: P25106 Research Area: Immunology, Signal Transduction
Description: Antibody raised against CXCR7-Specific

anti- CYP1A2-Specific antibody
FNab02148	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IP: 1:200-1:1000 IHC: 1:100-1:400 IF: 1:10-1:100 Immunogen: cytochrome P450, family 1, subfamily A, polypeptide 2 Uniprot ID: P05177 Gene ID: 1544 Research Area: Metabolism
Description: Antibody raised against CYP1A2-Specific

anti- CYP2E1-Specific antibody
FNab02159	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IF: 1:20-1:200 IHC: 1:20-1:200 Immunogen: cytochrome P450, family 2, subfamily E, polypeptide 1 Uniprot ID: P05181 Research Area: Cardiovascular, Metabolism
Description: Antibody raised against CYP2E1-Specific

anti- CYP4F11-Specific antibody
FNab02171	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: cytochrome P450, family 4, subfamily F, polypeptide 11 Uniprot ID: Q9HBI6 Research Area: Metabolism
Description: Antibody raised against CYP4F11-Specific

anti- CYP4Z1-Specific antibody
FNab02175	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 Immunogen: cytochrome P450, family 4, subfamily Z, polypeptide 1 Uniprot ID: Q86W10 Research Area: Metabolism
Description: Antibody raised against CYP4Z1-Specific

anti- DAPK2-Specific antibody
FNab02241	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 IF: 1:10-1:100 Immunogen: death-associated protein kinase 2 Uniprot ID: Q9UIK4 Research Area: Cardiovascular, Metabolism
Description: Antibody raised against DAPK2-Specific

anti- DCC-Specific antibody
FNab02262	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 Immunogen: deleted in colorectal carcinoma Uniprot ID: P43146 Gene ID: 1630 Research Area: Neuroscience, Cancer, Signal Transduction, Developmental biology
Description: Antibody raised against DCC-Specific

anti- DGKK-Specific antibody
FNab02360	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:2000 IF: 1:10-1:100 Immunogen: diacylglycerol kinase, kappa Uniprot ID: Q5KSL6 Research Area: Signal Transduction, Metabolism
Description: Antibody raised against DGKK-Specific

anti- DLL1-Specific antibody
FNab02415	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 Immunogen: delta-like 1(Drosophila) Uniprot ID: O00548 Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology
Description: Antibody raised against DLL1-Specific

anti- DOCK180-Specific antibody
FNab02493	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2400 IF: 1:10-1:100 Immunogen: dedicator of cytokinesis 1 Uniprot ID: Q14185 Research Area: Signal Transduction
Description: Antibody raised against DOCK180-Specific

anti- DR5-Specific antibody
FNab02530	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:2000 Immunogen: tumor necrosis factor receptor superfamily, member 10b Uniprot ID: O14763 Gene ID: 8795 Research Area: Immunology, Signal Transduction
Description: Antibody raised against DR5-Specific

anti- EDG7-Specific antibody
FNab02635	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: lysophosphatidic acid receptor 3 Uniprot ID: Q9UBY5 Research Area: Signal Transduction
Description: Antibody raised against EDG7-Specific

anti- EGFR-Specific antibody
FNab02669	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:2000-1:4000 IP: 1:500-1:1000 IHC: 1:200-1:800 IF: 1:50-1:500 Immunogen: epidermal growth factor receptor Uniprot ID: P00533 Gene ID: 1956 Research Area: Signal Transduction, Metabolism, Cardiovascular, Cancer, Immunolog Show more
Description: Antibody raised against EGFR-Specific

anti- EIF2C1-Specific antibody
FNab02697	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: eukaryotic translation initiation factor 2C, 1 Uniprot ID: Q9UL18 Gene ID: 26523 Research Area: Epigenetics, Metabolism
Description: Antibody raised against EIF2C1-Specific

anti- EIF2C3-Specific antibody
FNab02698	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 Immunogen: eukaryotic translation initiation factor 2C, 3 Uniprot ID: Q9H9G7 Research Area: Epigenetics, Metabolism
Description: Antibody raised against EIF2C3-Specific

anti- EPHA1-specific antibody
FNab02801	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IP: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:50-1:500 Immunogen: EPH receptor A1 Uniprot ID: P21709 Research Area: Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience
Description: Antibody raised against EPHA1-specific

anti- EPHA6-Specific antibody
FNab02804	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: EPH receptor A6 Uniprot ID: Q9UF33 Gene ID: 285220 Research Area: Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience
Description: Antibody raised against EPHA6-Specific

anti- FABP7-Specific antibody
FNab02937	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:1000-1:4000 IHC: 1:50-1:500 Immunogen: fatty acid binding protein 7, brain Uniprot ID: O15540 Research Area: Signal Transduction, Metabolism, Developmental biology, Neuroscience, Stem Cells
Description: Antibody raised against FABP7-Specific

anti- FANCA-Specific antibody
FNab03004	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 Immunogen: Fanconi anemia, complementation group A Uniprot ID: O15360 Research Area: Epigenetics, Metabolism
Description: Antibody raised against FANCA-Specific

anti- FcRn-Specific antibody
FNab03063	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 Immunogen: Fc fragment of IgG, receptor, transporter, alpha Uniprot ID: P55899 Gene ID: 2217 Research Area: Neuroscience
Description: Antibody raised against FcRn-Specific

anti- FGF16-Specific antibody
FNab03091	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 IHC: 1:20-1:200 Immunogen: fibroblast growth factor 16 Uniprot ID: O43320 Research Area: Immunology, Signal Transduction, Metabolism
Description: Antibody raised against FGF16-Specific

anti- FMO2-specific antibody
FNab03169	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 Immunogen: flavin containing monooxygenase 2(non-functional) Uniprot ID: Q99518 Gene ID: 2327 Research Area: Metabolism
Description: Antibody raised against FMO2-specific

anti- FMO5-specific antibody
FNab03171	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: flavin containing monooxygenase 5 Uniprot ID: P49326 Research Area: Metabolism
Description: Antibody raised against FMO5-specific

anti- FOXH1-Specific antibody
FNab03196	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 Immunogen: forkhead box H1 Uniprot ID: O75593 Research Area: Epigenetics, Signal Transduction, Metabolism, Developmental biology, Neuroscience
Description: Antibody raised against FOXH1-Specific

anti- FOXL2-Specific antibody
FNab03199	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 Immunogen: forkhead box L2 Uniprot ID: P58012 Research Area: Neuroscience, Signal Transduction, Metabolism, Developmental biology
Description: Antibody raised against FOXL2-Specific

anti- GAB3-Specific antibody
FNab03273	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:50-1:500 Immunogen: GRB2-associated binding protein 3 Uniprot ID: Q8WWW8 Research Area: Signal Transduction, Developmental biology
Description: Antibody raised against GAB3-Specific

anti- GABARAPL1-Specific antibody
FNab03276	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IP: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:20-1:200 Immunogen: GABA(A) receptor-associated protein like 1 Uniprot ID: Q9H0R8 Research Area: Neuroscience, Signal Transduction
Description: Antibody raised against GABARAPL1-Specific

anti- GABARAPL2-Specific antibody
FNab03278	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: GABA(A) receptor-associated protein-like 2 Uniprot ID: P60520 Research Area: Neuroscience, Signal Transduction
Description: Antibody raised against GABARAPL2-Specific

anti- GAC-specific antibody
FNab03290	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IP: 1:500-1:1000 IHC: 1:100-1:400 Immunogen: glutaminase Uniprot ID: O94925 Research Area: Neuroscience, Metabolism
Description: Antibody raised against GAC-specific

anti- ACADL-Specific antibody
FNab00064	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:2000 IHC: 1:20-1:200 Immunogen: acyl-Coenzyme A dehydrogenase, long chain Uniprot ID: P28330 Gene ID: 33 Research Area: Metabolism
Description: Antibody raised against ACADL-Specific

anti- ACTA1-Specific antibody
FNab00115	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:5000 IHC: 1:20-1:200 Immunogen: actin, alpha 1, skeletal muscle Uniprot ID: P68133 Gene ID: 58 Research Area: Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience, Cell Division and Proliferation
Description: Antibody raised against ACTA1-Specific

anti- ADAM17-Specific antibody
FNab00139	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:2000 IHC: 1:20-1:200 Immunogen: ADAM metallopeptidase domain 17 Uniprot ID: P78536 Gene ID: 6868 Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience
Description: Antibody raised against ADAM17-Specific

anti- ADRA1A-Specific antibody
FNab00177	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:2000 IHC: 1:20-1:500 Immunogen: adrenergic, alpha-1A-, receptor Uniprot ID: P35348 Gene ID: 148 Research Area: Neuroscience, Cardiovascular, Developmental biology, Signal Transduction
Description: Antibody raised against ADRA1A-Specific

anti- ADRA2B-Specific antibody
FNab00179	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 IHC: 1:50-1:500 Immunogen: adrenergic, alpha-2B-, receptor Uniprot ID: P18089 Gene ID: 151 Research Area: Signal Transduction
Description: Antibody raised against ADRA2B-Specific

anti- AFF1-Specific antibody
FNab00195	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:100 Immunogen: AF4/FMR2 family, member 1 Uniprot ID: P51825 Gene ID: 4299 Research Area: Cancer, Metabolism
Description: Antibody raised against AFF1-Specific

anti- AMPD1-Specific antibody
FNab00370	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:5000 Immunogen: adenosine monophosphate deaminase 1(isoform M) Uniprot ID: P23109 Gene ID: 270 Research Area: Metabolism
Description: Antibody raised against AMPD1-Specific

anti- ARF5-Specific antibody
FNab00534	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:3000 IF: 1:10-1:100 Immunogen: ADP-ribosylation factor 5 Uniprot ID: P62330 Gene ID: 381 Research Area: Metabolism
Description: Antibody raised against ARF5-Specific

anti- ARF6-Specific antibody
FNab00535	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 IF: 1:50-1:100 IHC: 1:50-1:500 Immunogen: ADP-ribosylation factor 6 Uniprot ID: P62330 Gene ID: 382 Research Area: Metabolism
Description: Antibody raised against ARF6-Specific

anti- ARHGEF9-Specific antibody
FNab00565	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 Immunogen: Cdc42 guanine nucleotide exchange factor(GEF) 9 Uniprot ID: O43307 Gene ID: 23229 Research Area: Neuroscience, Signal Transduction
Description: Antibody raised against ARHGEF9-Specific

anti- ARSK-Specific antibody
FNab00613	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 Immunogen: arylsulfatase family, member K Uniprot ID: Q6UWY0 Research Area: Metabolism
Description: Antibody raised against ARSK-Specific

anti- TMF1-Specific antibody
FNab08796	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:2000 IP: 1:200-1:1000 IHC: 1:20-1:200 Immunogen: TATA element modulatory factor 1 Uniprot ID: P82094 Research Area: Metabolism
Description: Antibody raised against TMF1-Specific

anti- TOP2A-Specific antibody
FNab08868	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:3000 IP: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: topoisomerase(DNA) II alpha 170kDa Uniprot ID: P11388 Research Area: Epigenetics, Cell Division and Proliferation, Metabolism
Description: Antibody raised against TOP2A-Specific

anti- Tuberin-Specific antibody
FNab09101	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:2000 IHC: 1:20-1:200；IF: 1:10-1:100 Immunogen: tuberous sclerosis 2 Uniprot ID: P49815 Gene ID: 7249 Research Area: Cell Division and Proliferation
Description: Antibody raised against Tuberin-Specific

anti- TWIST1-specific antibody
FNab09118	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 IP: 1:500-1:1000 Immunogen: twist homolog 1 Uniprot ID: Q15672 Research Area: Epigenetics, Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells
Description: Antibody raised against TWIST1-specific

anti- UBASH3A-Specific antibody
FNab09150	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:2000 IF: 1:10-1:100；IP: 1:200-1:2000 Immunogen: ubiquitin associated and SH3 domain containing, A Uniprot ID: P57075 Research Area: Metabolism
Description: Antibody raised against UBASH3A-Specific

anti- UBC9-Specific antibody
FNab09159	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:5000 IHC: 1:20-1:200；IF: 1:10-1:100 Immunogen: ubiquitin-conjugating enzyme E2I(UBC9 homolog, yeast) Uniprot ID: P63279 Research Area: Epigenetics, Metabolism, Developmental biology, Neuroscience, Cell Division an Show more
Description: Antibody raised against UBC9-Specific

anti- UBN1-Specific antibody
FNab09202	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:2000 IHC: 1:20-1:200 Immunogen: ubinuclein 1 Uniprot ID: Q9NPG3 Research Area: Metabolism
Description: Antibody raised against UBN1-Specific

anti- UNC5C-Specific antibody
FNab09263	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:5000 Immunogen: unc-5 homolog C(C. elegans) Uniprot ID: O95185 Research Area: Signal Transduction, Developmental biology
Description: Antibody raised against UNC5C-Specific

anti- UNC5D-Specific antibody
FNab09264	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:2000 Immunogen: unc-5 homolog D(C. elegans) Uniprot ID: Q6UXZ4 Research Area: Signal Transduction, Developmental biology
Description: Antibody raised against UNC5D-Specific

anti- URB1-Specific antibody
FNab09286	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:2000 Immunogen: URB1 ribosome biogenesis 1 homolog(S. cerevisiae) Uniprot ID: O60287 Research Area: Metabolism
Description: Antibody raised against URB1-Specific

anti- WASF4-Specific antibody
FNab09469	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:5000；IF: 1:10-1:100 Immunogen: WAS protein family, member 4 Uniprot ID: Q8IV90 Research Area: Metabolism
Description: Antibody raised against WASF4-Specific

anti- YES1-Specific antibody
FNab09563	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:2000 IP: 1:200-1:1000 IHC: 1:20-1:200 Immunogen: v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 Uniprot ID: P07947 Research Area: Cancer, Signal Transduction, Metabolism, Developmental biology
Description: Antibody raised against YES1-Specific

anti- ZIC4-Specific antibody
FNab09637	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:2000 Immunogen: Zic family member 4 Uniprot ID: Q8N9L1 Research Area: Neuroscience
Description: Antibody raised against ZIC4-Specific

anti- ZNF600-Specific antibody
FNab09718	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 Immunogen: zinc finger protein 600 Uniprot ID: Q6ZNG1 Research Area: Metabolism
Description: Antibody raised against ZNF600-Specific

anti- ZNRF2-Specific antibody
FNab09746	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 Immunogen: zinc and ring finger 2 Uniprot ID: Q8NHG8 Research Area: Neuroscience, Metabolism, Epigenetics
Description: Antibody raised against ZNRF2-Specific

anti- TUBB3 specific antibody
FNab09890	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:5000-1:50000 IHC: 1:50-1:500 Immunogen: AS160 Uniprot ID: Q13509 Gene ID: 10381 Research Area: Signal Transduction
Description: Antibody raised against TUBB3 specific

anti- GLI3-Specific antibody
FNab10099	FN Test	100µg	EUR 548.75
Recommended dilution: IHC: 1:50 - 1:500 Immunogen: GLI family zinc finger 3 Uniprot ID: P10071 Gene ID: 2737 Research Area: Neuroscience, Metabolism, Developmental biology
Description: Antibody raised against GLI3-Specific

anti- HIP1-Specific antibody
FNab03870	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:3000 IHC: 1:20-1:200 Immunogen: huntingtin interacting protein 1 Uniprot ID: O00291 Research Area: Neuroscience, Metabolism
Description: Antibody raised against HIP1-Specific

anti- HMMR-Specific antibody
FNab03936	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:50-1:500 IF: 1:10-1:100 Immunogen: hyaluronan-mediated motility receptor(RHAMM) Uniprot ID: O75330 Research Area: Immunology
Description: Antibody raised against HMMR-Specific

anti- HNRNPUL2-Specific antibody
FNab03961	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 IF: 1:50-1:500 Immunogen: heterogeneous nuclear ribonucleoprotein U-like 2 Uniprot ID: Q1KMD3 Research Area: Metabolism
Description: Antibody raised against HNRNPUL2-Specific

anti- HRAS-Specific antibody
FNab04008	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 IP:1:1000-1:6000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: v-Ha-ras Harvey rat sarcoma viral oncogene homolog Uniprot ID: P01112 Research Area: Cancer, Immunology, Signal Transduction, Cell Division and Proli Show more
Description: Antibody raised against HRAS-Specific

anti- HSPG2-Specific antibody
FNab04063	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 Immunogen: heparan sulfate proteoglycan 2 Uniprot ID: P98160 Research Area: Immunology, Cardiovascular, Signal Transduction
Description: Antibody raised against HSPG2-Specific

anti- IFITM1-Specific antibody
FNab04141	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:5000 - 1:50000 IHC: 1:200 - 1:1000 IP: 1:500 - 1:1000 Immunogen: interferon induced transmembrane protein 1(9-27) Uniprot ID: P13164 Research Area: Immunology, Signal Transduction
Description: Antibody raised against IFITM1-Specific

anti- IFITM2-specific antibody
FNab04143	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500 - 1:2000 Immunogen: interferon induced transmembrane protein 2 Uniprot ID: Q01629 Research Area: Immunology
Description: Antibody raised against IFITM2-specific

anti- IGF1B-Specific antibody
FNab04169	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500 - 1:2000 IHC: 1:20 - 1:200 Immunogen: insulin-like growth factor 1(somatomedin C) Uniprot ID: P05019 Gene ID: 3479 Research Area: Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience
Description: Antibody raised against IGF1B-Specific

anti- IGF2R-Specific antibody
FNab04174	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:1000-1:4000 IP: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:20-1:200 Immunogen: insulin-like growth factor 2 receptor Uniprot ID: P11717 Research Area: Cancer, Immunology, Signal Transduction
Description: Antibody raised against IGF2R-Specific

anti- ING1-specific antibody
FNab04309	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000；IP: 1:200-1:1000 Immunogen: inhibitor of growth family, member 1 Uniprot ID: Q9UK53 Research Area: Cancer
Description: Antibody raised against ING1-specific

anti- ING3-specific antibody
FNab04312	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2400 Immunogen: inhibitor of growth family, member 3 Uniprot ID: Q9NXR8 Research Area: Cancer, Metabolism
Description: Antibody raised against ING3-specific

anti- ING4-specific antibody
FNab04314	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IP: 1:200-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: inhibitor of growth family, member 4 Uniprot ID: Q9UNL4 Research Area: Cancer, Metabolism
Description: Antibody raised against ING4-specific

anti- ITPR1-specific antibody
FNab04425	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:50-1:500 Immunogen: inositol 1,4,5-triphosphate receptor, type 1 Uniprot ID: Q14643 Research Area: Neuroscience, Immunology, Signal Transduction
Description: Antibody raised against ITPR1-specific

anti- KCNB1-Specific antibody
FNab04480	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 IHC: 1:50-1:500 IF: 1:10-1:100 Immunogen: potassium voltage-gated channel, Shab-related subfamily, member 1 Uniprot ID: Q13303 Research Area: Neuroscience
Description: Antibody raised against KCNB1-Specific

anti- KGA-Specific antibody
FNab04520	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IP: 1:500-1:2000 IHC: 1:20-1:200 IF: 1:20-1:400 Immunogen: glutaminase Uniprot ID: O94925 Research Area: Neuroscience, Metabolism
Description: Antibody raised against KGA-Specific

anti- KISS1R-Specific antibody
FNab04593	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200 Immunogen: KISS1 receptor Uniprot ID: Q969F8 Gene ID: 84634 Research Area: Neuroscience, Signal Transduction
Description: Antibody raised against KISS1R-Specific

anti- KLHL14-Specific antibody
FNab04614	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 IF: 1:20-1:200 Immunogen: kelch-like 14(Drosophila) Uniprot ID: Q9P2G3 Research Area: Metabolism, Developmental biology
Description: Antibody raised against KLHL14-Specific

anti- KRT10-specific antibody
FNab04649	FN Test	100µg	EUR 548.75
Recommended dilution: IHC: 1:20-1:200 Immunogen: keratin 10 Uniprot ID: P13645 Research Area: Signal Transduction
Description: Antibody raised against KRT10-specific

anti- Kv1.4-Specific antibody
FNab04664	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:2000 Immunogen: potassium voltage-gated channel, shaker-related subfamily, member 4 Uniprot ID: P22459 Research Area: Neuroscience
Description: Antibody raised against Kv1.4-Specific

anti- LAMC3-Specific antibody
FNab04680	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500 - 1:1000 Immunogen: laminin, gamma 3 Uniprot ID: Q9Y6N6 Research Area: Signal Transduction
Description: Antibody raised against LAMC3-Specific

anti- LATS2-Specific antibody
FNab04709	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 IF: 1:20-1:200 Immunogen: LATS, large tumor suppressor, homolog 2 Uniprot ID: Q9NRM7 Gene ID: 26524 Research Area: Signal Transduction, Metabolism
Description: Antibody raised against LATS2-Specific

anti- LC3A-Specific antibody
FNab04719	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:1000-1:4000 IF: 1:10-1:100 Immunogen: microtubule-associated protein 1 light chain 3 alpha Uniprot ID: Q9H492 Gene ID: 84557 Research Area: Neuroscience, Cardiovascular, Metabolism
Description: Antibody raised against LC3A-Specific

anti- LC3B-Specific antibody
FNab04720	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200 Immunogen: microtubule-associated protein 1 light chain 3 beta Uniprot ID: Q9GZQ8 Gene ID: 81631 Research Area: Neuroscience, Cardiovascular, Metabolism
Description: Antibody raised against LC3B-Specific

anti- LDHA-Specific antibody
FNab04737	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:1000-1:4000 IP: 1:1000-1:4000 IHC: 1:20-1:200 IF: 1:20-1:200 Immunogen: lactate dehydrogenase A Uniprot ID: P00338 Gene ID: 3939 Research Area: Cardiovascular, Metabolism
Description: Antibody raised against LDHA-Specific

anti- LDHB-Specific antibody
FNab04739	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:3000 IHC: 1:100-1:400 IF: 1:10-1:100 Immunogen: lactate dehydrogenase B Uniprot ID: P07195 Research Area: Cancer, Metabolism
Description: Antibody raised against LDHB-Specific

anti- LDHC-Specific antibody
FNab04740	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: lactate dehydrogenase C Uniprot ID: P07864 Research Area: Metabolism
Description: Antibody raised against LDHC-Specific

anti- Lin28A-specific antibody
FNab04784	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 IHC: 1:20-1:200 Immunogen: lin-28 homolog(C. elegans) Uniprot ID: Q9H9Z2 Research Area: Neuroscience, Stem Cells, Metabolism, Epigenetics
Description: Antibody raised against Lin28A-specific

anti- Lin28B-specific antibody
FNab04786	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:5000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: lin-28 homolog B(C. elegans) Uniprot ID: Q6ZN17 Research Area: Epigenetics, Stem Cells, Metabolism
Description: Antibody raised against Lin28B-specific

anti- LRP2-Specific antibody
FNab04847	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 IHC: 1:100-1:400 Immunogen: low density lipoprotein-related protein 2 Uniprot ID: P98164 Research Area: Neuroscience, Metabolism, Developmental biology
Description: Antibody raised against LRP2-Specific

anti- MAS1L-Specific antibody
FNab05020	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:1000-1:4000 IF: 1:10-1:100 Immunogen: MAS1 oncogene-like Uniprot ID: P35410 Research Area: Cancer, Signal Transduction
Description: Antibody raised against MAS1L-Specific

anti- MCL1L-specific antibody
FNab05054	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: myeloid cell leukemia sequence 1(BCL2-related) Uniprot ID: Q07820 Research Area: Stem Cells, Cancer, Metabolism, Developmental biology
Description: Antibody raised against MCL1L-specific

anti- MDM1-Specific antibody
FNab05076	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 Immunogen: Mdm1 nuclear protein homolog(Mouse) Uniprot ID: Q8TC05 Research Area: Epigenetics, Metabolism, Immunology, Cancer, Cell Division and Proliferation
Description: Antibody raised against MDM1-Specific

anti- MEF2C-Specific antibody
FNab05107	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: myocyte enhancer factor 2C Uniprot ID: Q06413 Research Area: Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Stem Cells
Description: Antibody raised against MEF2C-Specific

anti- MYH10-Specific antibody
FNab05472	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:1000-1:4000 IP: 1:500-1:2000 IHC: 1:50-1:500 IF: 1:10-1:100 Immunogen: myosin, heavy chain 10, non-muscle Uniprot ID: P35580 Research Area: Cancer, Immunology, Developmental biology
Description: Antibody raised against MYH10-Specific

anti- MYH4-Specific antibody
FNab05476	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:200-1:1000 IHC: 1:20-1:200 Immunogen: myosin, heavy chain 4, skeletal muscle Uniprot ID: Q9Y623 Gene ID: 4621 Research Area: Cardiovascular, Immunology, Developmental biology, Neuroscience, Cell Division and Proliferation
Description: Antibody raised against MYH4-Specific

anti- MYH7-specific antibody
FNab05478	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: myosin, heavy chain 7, cardiac muscle, beta Uniprot ID: P12883 Research Area: Cardiovascular, Developmental biology, Neuroscience, Stem Cells, Cell Division and Proliferation
Description: Antibody raised against MYH7-specific

anti- MYOM1-Specific antibody
FNab05516	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: myomesin 1, 185kDa Uniprot ID: P52179 Research Area: Neuroscience, Cardiovascular, Developmental biology
Description: Antibody raised against MYOM1-Specific

anti- MYPN-Specific antibody
FNab05525	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: myopalladin Uniprot ID: Q86TC9 Research Area: Neuroscience
Description: Antibody raised against MYPN-Specific

anti- MYSM1-Specific antibody
FNab05527	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:300-1:600 IHC: 1:20-1:200 IF: 1:50-1:500 Immunogen: Myb-like, SWIRM and MPN domains 1 Uniprot ID: Q5VVJ2 Research Area: Metabolism
Description: Antibody raised against MYSM1-Specific

anti- NARFL-Specific antibody
FNab05553	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: nuclear prelamin A recognition factor-like Uniprot ID: Q9H6Q4 Research Area: Signal Transduction, Metabolism, Cell Division and Proliferation
Description: Antibody raised against NARFL-Specific

anti- NEB-Specific antibody
FNab05638	FN Test	100µg	EUR 548.75
Recommended dilution: IHC: 1:20-1:200 Immunogen: nebulin Uniprot ID: Q7Z6G3 Research Area: Neuroscience
Description: Antibody raised against NEB-Specific

anti- Neogenin-Specific antibody
FNab05662	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 Immunogen: neogenin homolog 1(chicken) Uniprot ID: Q92859 Research Area: Signal Transduction, Metabolism, Cancer, Immunology, Developmental biology
Description: Antibody raised against Neogenin-Specific

anti- GATA4-Specific antibody
FNab03363	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IP: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: GATA binding protein 4 Uniprot ID: P43694 Gene ID: 2626 Research Area: Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Stem Cell Show more
Description: Antibody raised against GATA4-Specific

anti- GEFT-Specific antibody
FNab03416	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:3000 IP: 1:500-1:3000 IHC: 1:20-1:200 Immunogen: RhoA/RAC/CDC42 exchange factor Uniprot ID: Q86VW2 Research Area: Neuroscience, Signal Transduction
Description: Antibody raised against GEFT-Specific

anti- GLI2-Specific antibody
FNab03477	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: GLI-Kruppel family member GLI2 Uniprot ID: P10070 Research Area: Stem Cells
Description: Antibody raised against GLI2-Specific

anti- GLI3-Specific antibody
FNab03478	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:200-1:1000 IP: 1:200-1:1000 IHC: 1:20-1:200 IF: 1:10-1:100 Immunogen: GLI family zinc finger 3 Uniprot ID: P10071 Gene ID: 2737 Research Area: Neuroscience, Metabolism, Developmental biology
Description: Antibody raised against GLI3-Specific

anti- GPR101-Specific antibody
FNab03587	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 Immunogen: G protein-coupled receptor 101 Uniprot ID: Q96P66 Research Area: Signal Transduction
Description: Antibody raised against GPR101-Specific

anti- GPR123-Specific antibody
FNab03592	FN Test	100µg	EUR 585
Recommended dilution: IHC: 1:20-1:200 Immunogen: G protein-coupled receptor 123 Uniprot ID: Q86SQ6 Research Area: Signal Transduction
Description: Antibody raised against GPR123-Specific

anti- GPR139-Specific antibody
FNab03596	FN Test	100µg	EUR 505.25
Recommended dilution: IHC: 1:20-1:200 Immunogen: G protein-coupled receptor 139 Uniprot ID: Q6DWJ6 Research Area: Signal Transduction
Description: Antibody raised against GPR139-Specific

anti- GPRASP1-Specific antibody
FNab03612	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:3000 IHC: 1:20-1:200 Immunogen: G protein-coupled receptor associated sorting protein 1 Uniprot ID: Q5JY77 Research Area: Signal Transduction
Description: Antibody raised against GPRASP1-Specific

anti- GPRIN3-Specific antibody
FNab03616	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 IF: 1:10-1:100 Immunogen: GPRIN family member 3 Uniprot ID: Q6ZVF9 Research Area: Neuroscience
Description: Antibody raised against GPRIN3-Specific

anti- HBA1-Specific antibody
FNab03767	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 IF: 1:50-1:500 Immunogen: hemoglobin, alpha 1 Uniprot ID: P69905 Research Area: Immunology
Description: Antibody raised against HBA1-Specific

anti- HBG1-Specific antibody
FNab03772	FN Test	100µg	EUR 585
Recommended dilution: IHC: 1:20-1:200 Immunogen: hemoglobin, gamma A Uniprot ID: P69891 Gene ID: 3047 Research Area: Immunology, Cardiovascular
Description: Antibody raised against HBG1-Specific

anti- HBM-Specific antibody
FNab03773	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 Immunogen: hemoglobin, mu Uniprot ID: Q6B0K9 Research Area: Immunology
Description: Antibody raised against HBM-Specific

anti- HBQ1-Specific antibody
FNab03776	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:1000-1:4000 Immunogen: hemoglobin, theta 1 Uniprot ID: P09105 Research Area: Immunology, Cardiovascular
Description: Antibody raised against HBQ1-Specific

anti- HBZ-Specific antibody
FNab03780	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:1000-1:4000 Immunogen: hemoglobin, zeta Uniprot ID: P02008 Research Area: Immunology
Description: Antibody raised against HBZ-Specific

anti- HDAC1-specific antibody
FNab03795	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IF: 1:10-1:100 Immunogen: histone deacetylase 1 Uniprot ID: Q13547 Research Area: Epigenetics, Cardiovascular, Metabolism
Description: Antibody raised against HDAC1-specific

anti- HDAC2-specific antibody
FNab03797	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IF: 1:10-1:100 IHC: 1:20-1:200 Immunogen: histone deacetylase 2 Uniprot ID: Q92769 Research Area: Epigenetics, Cardiovascular, Metabolism
Description: Antibody raised against HDAC2-specific

anti- HDAC3-specific antibody
FNab03799	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 Immunogen: histone deacetylase 3 Uniprot ID: O15379 Research Area: Epigenetics, Cardiovascular, Metabolism
Description: Antibody raised against HDAC3-specific

anti- HDAC4-specific antibody
FNab03801	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IP: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: histone deacetylase 4 Uniprot ID: P56524 Research Area: Epigenetics, Cardiovascular, Metabolism, Developmental biology
Description: Antibody raised against HDAC4-specific

anti- HDAC5-specific antibody
FNab03802	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:200-1:1000 IF: 1:50-1:500 IHC: 1:20-1:200 Immunogen: histone deacetylase 5 Uniprot ID: Q9UQL6 Gene ID: 51020 Research Area: Epigenetics, Cardiovascular, Metabolism
Description: Antibody raised against HDAC5-specific

anti- HDAC6-specific antibody
FNab03804	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 Immunogen: histone deacetylase 6 Uniprot ID: Q9UBN7 Gene ID: 10013 Research Area: Epigenetics, Metabolism
Description: Antibody raised against HDAC6-specific

anti- neurturin-Specific antibody
FNab05683	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: neurturin Uniprot ID: Q99748 Research Area: Neuroscience, Signal Transduction, Developmental biology
Description: Antibody raised against neurturin-Specific

anti- NFIX-Specific antibody
FNab05701	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 Immunogen: nuclear factor I/X(CCAAT-binding transcription factor) Uniprot ID: Q14938 Research Area: Neuroscience, Epigenetics
Description: Antibody raised against NFIX-Specific

anti- NOX3-Specific antibody
FNab05805	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:1000 Immunogen: NADPH oxidase 3 Uniprot ID: Q9HBY0 Research Area: Metabolism
Description: Antibody raised against NOX3-Specific

anti- OCT2-Specific antibody
FNab05962	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IHC: 1:20-1:200 Immunogen: POU class 2 homeobox 2 Uniprot ID: P09086 Gene ID: 5452 Research Area: Cancer, Immunology, Metabolism, Developmental biology
Description: Antibody raised against OCT2-Specific

anti- Oct6-Specific antibody
FNab05965	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 Immunogen: POU class 3 homeobox 1 Uniprot ID: Q86VW1 Research Area: Neuroscience, Metabolism, Developmental biology
Description: Antibody raised against Oct6-Specific

anti- ORM2-Specific antibody
FNab06014	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:5000 IF: 1:50-1:500 Immunogen: orosomucoid 2 Uniprot ID: P19652 Research Area: Cardiovascular
Description: Antibody raised against ORM2-Specific

anti- PACS2-Specific antibody
FNab06099	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:1000 IHC: 1:50-1:500 IF: 1:10-1:100 Immunogen: phosphofurin acidic cluster sorting protein 2 Uniprot ID: Q86VP3 Research Area: Cell Division and Proliferation
Description: Antibody raised against PACS2-Specific

anti- Palladin-Specific antibody
FNab06127	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 IP: 1:200-1:1000 Immunogen: palladin, cytoskeletal associated protein Uniprot ID: Q8WX93 Research Area: Neuroscience, Immunology
Description: Antibody raised against Palladin-Specific

anti- PAX1-Specific antibody
FNab06167	FN Test	100µg	EUR 548.75
Recommended dilution: WB: 1:500-1:2000 Immunogen: paired box 1 Uniprot ID: P15863 Research Area: Metabolism, Developmental biology
Description: Antibody raised against PAX1-Specific

anti- PAX8-Specific antibody
FNab06177	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: paired box 8 Uniprot ID: Q06710 Research Area: Cancer, Immunology, Metabolism, Developmental biology
Description: Antibody raised against PAX8-Specific

anti- persephin-Specific antibody
FNab06323	FN Test	100µg	EUR 585
Recommended dilution: WB: 1:500-1:1000 IHC: 1:20-1:200 Immunogen: persephin Uniprot ID: O60542 Research Area: Neuroscience, Developmental biology
Description: Antibody raised against persephin-Specific

anti- PFKFB3-Specific antibody
FNab06339	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:20-1:200 Immunogen: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Uniprot ID: Q16875 Gene ID: 5209 Research Area: Metabolism
Description: Antibody raised against PFKFB3-Specific

Induction of protecting immune responses in opposition to a deadly Zika virus problem post-vaccination with a twin serotype of recombinant vesicular stomatitis virus carrying the genetically modified Zika virus E protein gene

The event of a vaccine to forestall Zika virus (ZIKV) an infection has been one of many priorities in infectious illness analysis lately. There have been quite a few makes an attempt to develop an efficient vaccine in opposition to ZIKV. It’s crucial to decide on the most secure and the best ZIKV vaccine from all candidate vaccines to manage this an infection globally. We’ve employed a twin serotype of prime-boost recombinant vesicular stomatitis virus (VSV) vaccine technique, to develop a ZIKV vaccine candidate, utilizing a kind 1 IFN-receptor knock-out (Ifnar ^-/-) mouse mannequin for problem research.

Prime vaccination with an attenuated recombinant VSV Indiana serotype (rVSV_Ind) carrying a genetically modified ZIKV envelope (E) protein gene adopted by enhance vaccination with attenuated recombinant VSV New Jersey serotype (rVSV_NJ) carrying the identical E gene induced sturdy adaptive immune responses. Particularly, rVSV carrying the ZIKV E gene with the honeybee melittin sign peptide (msp) on the N terminus and VSV G protein transmembrane area and cytoplasmic tail (Gtc) on the C terminus of the E gene induced robust protecting immune responses. This vaccine routine induced extremely potent neutralizing antibodies and T cell responses within the absence of an adjuvant and guarded Ifnar ^-/- mice from a deadly dose of the ZIKV problem.

Chilly-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β manufacturing 

Background: Gout is an autoinflammatory illness pushed by interleukin-1 (IL-1) induction in response to uric acid crystals. IL-1β manufacturing relies on inflammasome activation, which requires a priming sign, adopted by an activating sign. The cold-inducible RNA-binding protein (CIRP) has been not too long ago recognized as a damage-associated molecular sample (DAMP). On this research, we evaluated the roles of CIRP in monosodium urate (MSU)-mediated IL-1β secretion utilizing human neutrophils. 

Strategies: Human neutrophils had been stimulated by MSU within the presence or absence of CIRP priming to find out NLRP3 inflammasome activation and subsequent caspase-1 activation and IL-1β manufacturing. Mobile supernatants had been analyzed by enzyme-linked immunosorbent assay (ELISA) to find out the presence of IL-1β or caspase-1 (p20). The mobile supernatants and lysates had been additionally analyzed by immunoblotting utilizing anti-cleaved IL-1β or anti-cleaved caspase-1 antibodies.

Outcomes: Neither CIRP nor MSU stimulation alone induced ample IL-1β secretion from neutrophils. Nevertheless, MSU stimulation induced IL-1β secretion from CIRP-primed neutrophils in a dose-dependent method. This MSU-induced IL-1β secretion from CIRP-primed neutrophils was accompanied by the induction of cleaved IL-1β (p17), which was inhibited by the pretreatment of MCC950, a selected inhibitor for NLRP3. Moreover, cleaved caspase-1 was induced within the mobile lysates of CIRP/MSU-treated neutrophils. Moreover, CIRP stimulation induced the protein expression of pro-IL-1β in neutrophils. 

Conclusions: Our knowledge point out that CIRP, an endogenous stress molecule, triggers uric acid-induced mature IL-1β induction as a priming stimulus for NLRP3 inflammasome in human neutrophils. We suggest that CIRP acts as an necessary proinflammatory stimulant that primes and prompts inflammasome and pro-IL-1β processing in response to uric acid in innate immune cells.

Active Human Caspases Group I, Active Human
K241-3-25	Biovision		EUR 370

HDAC-8, human recombinant
7618-100	Biovision		EUR 588

HDAC-8, human recombinant
7618-1000	Biovision		EUR 4345

HDAC-8, human recombinant
7618-20	Biovision		EUR 262

Anti-active Caspase-3 Rabbit Monoclonal Antibody
M00334-3	BosterBio	100ug/vial	EUR 397
Description: Anti-active Caspase-3 Rabbit Monoclonal Antibody tested for IF, IHC, ICC, WB in Human

CST3 Mouse, Cystatin-C, Recombinant Protein Mouse Active
PROTP21460-3	BosterBio	Regular: 10ug	EUR 317
Description: CST3 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 126 amino acids (21-140 a.a.) and having a molecular mass of 14.2kDa (Molecular size on SDS-PAGE will appear at approximately 13.5-18kDa).;CST3 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

HDAC 3 antibody
20R-1663	Fitzgerald	100 ug	EUR 673
Description: Rabbit polyclonal HDAC 3 antibody

HDAC-IN-3
HY-19772	MedChemExpress	50mg	EUR 2116

NCOR2/ Rat NCOR2 ELISA Kit
ELA-E11288r	Lifescience Market	96 Tests	EUR 886

HDAC 3 Blocking Peptide
33R-10518	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 3 antibody, catalog no. 20R-1663

HDAC-3 Blocking Peptide
3603BP-50	Biovision		EUR 153

Recombinant Human MMP-3 Protein
PROTP08254-3	BosterBio	10ug	EUR 317
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids).

NCOR2 antibody
70R-18789	Fitzgerald	50 ul	EUR 435
Description: Rabbit polyclonal NCOR2 antibody

NCOR2 Antibody
43109-100ul	SAB	100ul	EUR 252

NCOR2 Antibody
1-CSB-PA080039	Cusabio	EUR 222.00 EUR 195.00	100ug 50ug
Form: Liquid Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against NCOR2. Recognizes NCOR2 from Human. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/20000

NCOR2 Antibody
DF8896	Affbiotech	200ul	EUR 304
Description: NCOR2 Antibody detects endogenous levels of total NCOR2.

NCOR2 Antibody
1-CSB-PA015548GA01HU	Cusabio	EUR 597.00 EUR 333.00	150ul 50ul
Form: Liquid Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles. Antigen Affinity purified
Description: A polyclonal antibody against NCOR2. Recognizes NCOR2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

NCOR2 antibody
70R-32241	Fitzgerald	100 ug	EUR 327
Description: Rabbit polyclonal NCOR2 antibody

NCOR2 siRNA
20-abx925532	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol
Shipped within 5-10 working days.

NCOR2 siRNA
20-abx925533	Abbexa	EUR 551.00 EUR 732.00	15 nmol 30 nmol
Shipped within 5-10 working days.

NCOR2 Antibody
ABD8896	Lifescience Market	100 ug	EUR 438

NCOR2 antibody
PAab10069	Lifescience Market	100 ug	EUR 386

anti-NCOR2
YF-PA25381	Abfrontier	50 ul	EUR 334
Description: Mouse polyclonal to NCOR2

HDAC ELISA KIT|Human
EF010966	Lifescience Market	96 Tests	EUR 689

IL-3 Interleukin-3 Human Recombinant Protein, His Tag
PROTP08700-3	BosterBio	Regular: 50ug	EUR 317
Description: Interleukin-3 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 154 amino acids fragment (20-152) and having a total molecular mass of 17.3kDa and fused with a 20 aa N-terminal His tag. ;The IL3 His is purified by proprietary chromatographic techniques.

Human NCOR2 ELISA Kit
ELA-E0334h	Lifescience Market	96 Tests	EUR 824

NCOR2 ELISA KIT|Human
EF000574	Lifescience Market	96 Tests	EUR 689

Human NCOR2 shRNA Plasmid
20-abx956396	Abbexa	EUR 801.00 EUR 1121.00	150 µg 300 µg
Shipped within 15-20 working days.

NCOR2 sgRNA CRISPR Lentivector (Human) (Target 3)
K1400604	ABM	1.0 ug DNA	EUR 154

PRMT1, human recombinant (Active)
4865-10	Biovision		EUR 153

PRMT1, human recombinant (Active)
4865-1000	Biovision		EUR 3834

PRMT1, human recombinant (Active)
4865-50	Biovision		EUR 392

Active AHCY, human recombinant
7527-10	Biovision		EUR 262

Active AHCY, human recombinant
7527-1000	Biovision		EUR 5482

Active AHCY, human recombinant
7527-50	Biovision		EUR 479

Active Recombinant Human CETP
7606-100	Biovision		EUR 805

Active Recombinant Human CETP
7606-1000	Biovision		EUR 4345

Active Recombinant Human CETP
7606-20	Biovision		EUR 262

Active SIRT2, human recombinant
7698-10	Biovision		EUR 262

Active SIRT2, human recombinant
7698-1000	Biovision		EUR 4394

Active SIRT2, human recombinant
7698-50	Biovision		EUR 457

Active SIRT7, human recombinant
7846-10	Biovision		EUR 218

Active SIRT7, human recombinant
7846-50	Biovision		EUR 588

Irisin, Active, human recombinant
7852-10	Biovision		EUR 370

Irisin, Active, human recombinant
7852-50	Biovision		EUR 1077

HER2, Active, Human Recombinant
8011-5	Biovision		EUR 240

HER2, Active, Human Recombinant
8011-50	Biovision		EUR 1132

GAPDH, Active, human recombinant
P1100-10	Biovision		EUR 142

GAPDH, Active, human recombinant
P1100-50	Biovision		EUR 392

HDAC Substrate, Colorimetric
2207-100	Biovision		EUR 300

HDAC Substrate, Colorimetric
2207-25	Biovision		EUR 126

HDAC Substrate, Fluorogenic
2396-25	Biovision		EUR 512

HDAC Substrate, Fluorogenic
2396-5	Biovision		EUR 175

HDAC 1 antibody
20R-1661	Fitzgerald	100 ug	EUR 673
Description: Rabbit polyclonal HDAC 1 antibody

HDAC 2 antibody
20R-1662	Fitzgerald	100 ug	EUR 673
Description: Rabbit polyclonal HDAC 2 antibody

HDAC 4 antibody
20R-1664	Fitzgerald	100 ug	EUR 662
Description: Rabbit polyclonal HDAC 4 antibody

HDAC 4 antibody
20R-1665	Fitzgerald	100 ug	EUR 673
Description: Rabbit polyclonal HDAC 4 antibody

HDAC 5 antibody
20R-1666	Fitzgerald	100 ug	EUR 662
Description: Rabbit polyclonal HDAC 5 antibody

HDAC 6 antibody
20R-1667	Fitzgerald	100 ug	EUR 629
Description: Rabbit polyclonal HDAC 6 antibody

HDAC 7 antibody
20R-1668	Fitzgerald	100 ug	EUR 629
Description: Rabbit polyclonal HDAC 7 antibody

HDAC 8 antibody
20R-1669	Fitzgerald	100 ug	EUR 629
Description: Rabbit polyclonal HDAC 8 antibody

HDAC 9 antibody
20R-1670	Fitzgerald	100 ug	EUR 651
Description: Rabbit polyclonal HDAC 9 antibody

HDAC 10 antibody
20R-1671	Fitzgerald	100 ug	EUR 629
Description: Rabbit polyclonal HDAC 10 antibody

HDAC 11 antibody
20R-1672	Fitzgerald	100 ug	EUR 651
Description: Rabbit polyclonal HDAC 11 antibody

HDAC Assay Kit
55R-1371	Fitzgerald	100 assays	EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HDAC Assay Kit
55R-1372	Fitzgerald	100 assays	EUR 673
Description: Assay Kit for detection of HDAC in the research laboratory

HDAC Set I
A9906-1	ApexBio	1 Set	EUR 154

HDAC-IN-7
HY-13592	MedChemExpress	10mM/1mL	EUR 215

Apicidin (HDAC inhibitor)
SIH-346-1MG	Stressmarq	1 mg	EUR 136
Cyclopeptide inhibitor of histone deactylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1? protein levels and transcriptional activity in human and mouse t Show more
Description: The substance Apicidin is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble in 10 mg/ml DMSO or 100% Ethanol.

Apicidin (HDAC inhibitor)
SIH-346-5MG	Stressmarq	5 mg	EUR 340
Cyclopeptide inhibitor of histone deactylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1? protein levels and transcriptional activity in human and mouse t Show more
Description: The substance Apicidin is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble in 10 mg/ml DMSO or 100% Ethanol.

HPA (HDAC inhibitor)
SIH-356-10MG	Stressmarq	10 mg	EUR 128
Histone deacetylase (HDAC) inhibitor, IC50=13 µM Histone deacetylase (HDAC) inhibitor, IC50=13 µM
Description: The substance HPA is a hdac inhibitor. It is synthetically produced and has a purity of >97%. The pure substance is colorless oil which is soluble in 25 mg/ml DMSO or 25 mg/ml Ethanol.

HPA (HDAC inhibitor)
SIH-356-50MG	Stressmarq	50 mg	EUR 226
Histone deacetylase (HDAC) inhibitor, IC50=13 µM Histone deacetylase (HDAC) inhibitor, IC50=13 µM
Description: The substance HPA is a hdac inhibitor. It is synthetically produced and has a purity of >97%. The pure substance is colorless oil which is soluble in 25 mg/ml DMSO or 25 mg/ml Ethanol.

PLGF3 Human, Placenta Growth Factor-3 Human Recombinant Protein, sf9
PROTP49763-3	BosterBio	Regular: 25ug	EUR 317
Description: PLGF3 Human Recombinant produced in Spodoptera frugiperda is a glycosylated homodimer containing 2 chains of 203 amino acids (Leu19-Arg221) and having a molecular mass of 58kDa.;The PLGF-3 is purified by proprietary chromatographic techniques.

NCOR2 Blocking Peptide
DF8896-BP	Affbiotech	1mg	EUR 195

NCOR2 Conjugated Antibody
C43109	SAB	100ul	EUR 397

NCOR2 Rabbit pAb
A8388-100ul	Abclonal	100 ul	EUR 308

NCOR2 Rabbit pAb
A8388-200ul	Abclonal	200 ul	EUR 459

NCOR2 Rabbit pAb
A8388-20ul	Abclonal	20 ul	EUR 183

NCOR2 Rabbit pAb
A8388-50ul	Abclonal	50 ul	EUR 223

anti- NCOR2 antibody
FNab10069	FN Test	100µg	EUR 548.75
Recommended dilution: IHC: 1:20-1:200 Immunogen: nuclear receptor co-repressor 2 Uniprot ID: Q9Y618 Gene ID: 9612 Research Area: Metabolism
Description: Antibody raised against NCOR2

anti- NCOR2 antibody
FNab05594	FN Test	100µg	EUR 505.25
Recommended dilution: WB: 1:500 - 1:2000 IF: 1:50 - 1:100 Immunogen: nuclear receptor co-repressor 2 Uniprot ID: Q9Y618 Gene ID: 9612 Research Area: Metabolism
Description: Antibody raised against NCOR2

Anti-NCOR2 antibody
PAab05594	Lifescience Market	100 ug	EUR 355

Anti-NCOR2 antibody
STJ110686	St John's Laboratory	100 µl	EUR 277
Description: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant
PROTP10600-3	BosterBio	Regular: 5ug	EUR 317
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques.

NCOR2 ORF Vector (Human) (pORF)
ORF025977	ABM	1.0 ug DNA	EUR 2730

NCOR2 ELISA Kit (Human) (OKEH04298)
OKEH04298	Aviva Systems Biology	96 Wells	EUR 662
Description: Description of target: This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 100 pg/mL

Human recombinant UBE2D3
6430-3	Biovision		EUR 365

Human recombinant UBE2L3
6431-3	Biovision		EUR 365

LIGHT, Human Recombinant
P1291-3	Biovision		EUR 175

Recombinant Human Assembly Protein Complex 3
7-04360	CHI Scientific	2µg	Ask for price

Recombinant Human Assembly Protein Complex 3
7-04361	CHI Scientific	10µg	Ask for price

Recombinant Human Assembly Protein Complex 3
7-04362	CHI Scientific	1mg	Ask for price

Recombinant Human Activin-A Active
7-00004	CHI Scientific	1ug	Ask for price

Recombinant Human Activin-A Active
7-00005	CHI Scientific	5ug	Ask for price

Recombinant Human Activin-A Active
7-00006	CHI Scientific	100µg	Ask for price

Recombinant Human Activin-B Active
7-00010	CHI Scientific	1ug	Ask for price

Recombinant Human Activin-B Active
7-00011	CHI Scientific	5ug	Ask for price

Recombinant Human Activin-B Active
7-00012	CHI Scientific	100µg	Ask for price

Active Cathepsin S, human recombinant
7526-10	Biovision		EUR 338

Active Cathepsin S, human recombinant
7526-50	Biovision		EUR 1126

Active Cathepsin S, human recombinant
7526-500	Biovision		EUR 9130

Active Cathepsin B, human recombinant
7580-1000	Biovision		EUR 9783

Active Cathepsin B, human recombinant
7580-5	Biovision		EUR 294

Active Cathepsin B, human recombinant
7580-50	Biovision		EUR 1132

Cathepsin K, Active, human recombinant
7600-5	Biovision		EUR 392

Cathepsin K, Active, human recombinant
7600-50	Biovision		EUR 2279

MMP-9, Active, human recombinant
7867-1000	Biovision		EUR 501

MMP-9, Active, human recombinant
7867-500	Biovision		EUR 332

Active BCL2L1 Protein, human recombinant
7885-10	Biovision		EUR 256

Active BCL2L1 Protein, human recombinant
7885-50	Biovision		EUR 691

MMP-14, Active, Human Recombinant
8009-10	Biovision		EUR 316

MMP-14, Active, Human Recombinant
8009-50	Biovision		EUR 805

Active Cathepsin D, Human Recombinant
9229-10	Biovision		EUR 245

Active Cathepsin D, Human Recombinant
9229-100	Biovision		EUR 1132

Active Cathepsin D, Human Recombinant
9229-50	Biovision		EUR 735

5-Lipoxygenase, Active, Human Recombinant
P1373-200	Biovision		EUR 316

MMP-9, Active, Human Recombinant
P1567-10	Biovision	10 µg	EUR 348

MMP-9, Active, Human Recombinant
P1567-50	Biovision	50 µg	EUR 510

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03937	CHI Scientific	3µg	Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03938	CHI Scientific	10µg	Ask for price

Recombinant Human Mitogen-Activated Protein Kinase 3, Active
7-03939	CHI Scientific	20µg	Ask for price

HDAC Substrate II, Colorimetric
2395-25	Biovision		EUR 457

HDAC Substrate II, Colorimetric
2395-5	Biovision		EUR 153

AR-42 (HDAC-42)
2716-1	Biovision		EUR 153

AR-42 (HDAC-42)
2716-5	Biovision		EUR 457

HDAC 1 Blocking Peptide
33R-10516	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 1 antibody, catalog no. 20R-1661

HDAC 2 Blocking Peptide
33R-10517	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 2 antibody, catalog no. 20R-1662

HDAC 4 Blocking Peptide
33R-10519	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 4 antibody, catalog no. 20R-1664

HDAC 5 Blocking Peptide
33R-10520	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 5 antibody, catalog no. 20R-1666

HDAC 6 Blocking Peptide
33R-10521	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 6 antibody, catalog no. 20R-1667

HDAC 7 Blocking Peptide
33R-10522	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 7 antibody, catalog no. 20R-1668

HDAC 8 Blocking Peptide
33R-10523	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 8 antibody, catalog no. 20R-1669

HDAC 9 Blocking Peptide
33R-10524	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 9 antibody, catalog no. 20R-1670

HDAC 10 Blocking Peptide
33R-10525	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 10 antibody, catalog no. 20R-1671

HDAC 11 Blocking Peptide
33R-10526	Fitzgerald	50 ug	EUR 349
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HDAC 11 antibody, catalog no. 20R-1672

HDAC-1 Blocking Peptide
3601BP-50	Biovision		EUR 153

HDAC-2 Blocking Peptide
3602BP-50	Biovision		EUR 153

HDAC-4 Blocking Peptide
3604BP-50	Biovision		EUR 153

HDAC-5 Blocking Peptide
3605BP-50	Biovision		EUR 153

HDAC-6 Blocking Peptide
3606BP-50	Biovision		EUR 153

HDAC-7 Blocking Peptide
3607BP-50	Biovision		EUR 153

HDAC-8 Blocking Peptide
3608BP-50	Biovision		EUR 153

HDAC-9 Blocking Peptide
3609BP-50	Biovision		EUR 153

HDAC-10 Blocking Peptide
3610BP-50	Biovision		EUR 153

HDAC-11 Blocking Peptide
3611BP-50	Biovision		EUR 153

JAK/HDAC-IN-1
HY-126141	MedChemExpress	10mM/1mL	EUR 239

DiscoveryPak? HDAC Inhibitor Set
K851-6	Biovision		EUR 686

HDAC Family Antibody Set
K333-11-30	Biovision		EUR 1240

Trichostatin A (HDAC inhibitor)
SIH-254-1MG	Stressmarq	1 mg	EUR 206
Trichostatin A is an antifungal and selectively inhibits the class I and II mammalian histon deacetlyase families of enzymes (1). TSA inhibits the eukayotic cell cycle during the beginning of the growth stage. It can be used to alter gene expression Show more
Description: The substance Trichostatin A is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is beige solid which is soluble to 10 mM in ethanol and to 50 mM in DMSO.

Trichostatin A (HDAC inhibitor)
SIH-254-5MG	Stressmarq	5 mg	EUR 613
Trichostatin A is an antifungal and selectively inhibits the class I and II mammalian histon deacetlyase families of enzymes (1). TSA inhibits the eukayotic cell cycle during the beginning of the growth stage. It can be used to alter gene expression Show more
Description: The substance Trichostatin A is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is beige solid which is soluble to 10 mM in ethanol and to 50 mM in DMSO.

Phenylbutyrate Na (HDAC inhibitor)
SIH-255-100MG	Stressmarq	100 mg	EUR 93
Sodium phenylbutyrate is metabolized in the human body by beta-oxidation to phenylacetate, which is then conjugated with glutamine to phenylacetylglutamine, which is eliminated with urine (1). It inhibits cell proliferation, invasion and migration an Show more
Description: The substance Phenylbutyrate Na is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 1100 mM in water and 100 mM in DMSO.

Phenylbutyrate Na (HDAC inhibitor)
SIH-255-500MG	Stressmarq	500 mg	EUR 127
Sodium phenylbutyrate is metabolized in the human body by beta-oxidation to phenylacetate, which is then conjugated with glutamine to phenylacetylglutamine, which is eliminated with urine (1). It inhibits cell proliferation, invasion and migration an Show more
Description: The substance Phenylbutyrate Na is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 1100 mM in water and 100 mM in DMSO.

Bml-210 (HDAC inhibitor)
SIH-348-25MG	Stressmarq	25 mg	EUR 866
A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.
Description: The substance Bml-210 is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol.

Bml-210 (HDAC inhibitor)
SIH-348-5MG	Stressmarq	5 mg	EUR 266
A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.
Description: The substance Bml-210 is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol.

Sodium Valproate (HDAC inhibitor)
SIH-357-5G	Stressmarq	5 g	EUR 95
Histone deacetylase inhibitor (IC50=400 µM). Demonstrates neuroprotective, anticancer and anti-inflammatory activity. Inhibits A? production and neuritic plaque formation in Alzheimer's mouse models. Clinically useful anticonvulsant.
Description: The substance Sodium Valproate is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble in 50 mg/ml Water.

SAHA (Vorinostat) (HDAC inhibitor)
SIH-359-250MG	Stressmarq	250 mg	EUR 329
Potent and selective histone deacetylase inhibitor. Induces apoptosis in a variety of tumor cell lines. Synergizes with kinase inhibitors to kill CNS tumor cells. Cell permeable.
Description: The substance SAHA (Vorinostat) is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble in 50 mg/ml DMSO, or 2 mg/ml Ethanol.

SAHA (Vorinostat) (HDAC inhibitor)
SIH-359-50MG	Stressmarq	50 mg	EUR 128
Potent and selective histone deacetylase inhibitor. Induces apoptosis in a variety of tumor cell lines. Synergizes with kinase inhibitors to kill CNS tumor cells. Cell permeable.
Description: The substance SAHA (Vorinostat) is a hdac inhibitor. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble in 50 mg/ml DMSO, or 2 mg/ml Ethanol.

MS 275 (HDAC inhibitor)
SIH-416-1MG	Stressmarq	1 mg	EUR 171
MS 275, also referred to as Entinostat, is a benzamide histone deacetylase inhibitor. It preferentially inhibits HDAC1 and HDAC3. It is currently undergoing several clinical trials for the treatment of Hodgkin's lymphoma, advanced breast cancer, and Show more
Description: The substance MS 275 is a hdac inhibitor. It is synthetically produced and has a purity of >98.5. The pure substance is off white solid which is soluble in DMSO or methanol..

Active Blocker 3
abx090803-01g	Abbexa	0.1 g	EUR 411
Shipped within 5-10 working days.

Caspase-3, active
RA15046	Neuromics	50 ug	EUR 383

ANGPTL3 (17-460)Human Angiopoietin-like Protein 3 (17-460 a.a.) Human Recombinant Protein
PROTQ9Y5C1-3	BosterBio	Regular: 10ug	EUR 317
Description: ANGPTL3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 453 amino acids (17-460 a.a.) and having a molecular mass of 52.9kDa (Migrates at 25-70kDa on SDS-PAGE under reducing conditions).

Human recombinant UBE2R1 (CDC34)
6436-3	Biovision		EUR 365

Human recombinant UBE2R2 (Ubc3B)
6437-3	Biovision		EUR 392

Human recombinant UBE2E2 (UbcH8)
6438-3	Biovision		EUR 392

sIL-4R?, Human Recombinant
P1287-3	Biovision		EUR 175

Recombinant Human Sox2 Protein
PROTP48431-3	BosterBio	25ug	EUR 317
Description: Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF-4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology, gene expression, and in the capacity to form teratomas in immune-deficient mice. Recombinant human Sox2 is a 34.3 kDa protein containing 317 amino-acid residues.