DEFICIENCY OF MYELOID PHD PROTEINS AGGRAVATES ATHEROGENESIS

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DEFICIENCY OF MYELOID PHD PROTEINS AGGRAVATES ATHEROGENESIS VIA MACROPHAGE APOPTOSIS AND PARACRINE FIBROTIC SIGNALING: Atherogenic results of myeloid PHD knockdown

Goals: Atherosclerotic plaque hypoxia is detrimental for macrophage operate. Prolyl hydroxylases (PHDs) provoke mobile hypoxic responses, presumably influencing macrophage operate in plaque hypoxia. Thus, we aimed to elucidate the position of myeloid PHDs in atherosclerosis.

Strategies & outcomes: Myeloid particular PHD knockout (PHDko) mice had been obtained through bone marrow transplantation (PHD1ko, PHD3ko) or conditional knockdown by means of lysozyme M-driven Cre recombinase (PHD2cko). Mice had been fed excessive ldl cholesterol eating regimen for 6-12 weeks to induce atherosclerosis. Aortic root plaque measurement was considerably augmented 2.6-fold in PHD2cko, and 1.4-fold in PHD3ko in comparison with controls, however was unchanged in PHD1ko mice. Macrophage apoptosis was promoted in PHD2cko and PHD3ko mice in vitro and in vivo, through the HIF1α/BNIP3 axis. Bulk and single cell RNA knowledge of PHD2cko bone-marrow-derived macrophages (BMDM) and plaque macrophages, respectively, confirmed enhanced HIF1α/BNIP3 signaling, which was validated in vitro by siRNA silencing. Human plaque BNIP3 mRNA was positively related to plaque necrotic core measurement, suggesting comparable pro-apoptotic results in human.

Additional, PHD2cko plaques displayed enhanced fibrosis, whereas macrophage collagen breakdown by matrix metalloproteinases, collagen manufacturing and proliferation had been unaltered. As an alternative, PHD2cko BMDMs enhanced fibroblast collagen secretion in a paracrine method. In silico evaluation of macrophage-fibroblast communication predicted SPP1 (osteopontin) signaling as regulator, which was corroborated by enhanced plaque SPP1 protein in vivo. Elevated SPP1 mRNA expression upon PHD2cko was preferentially noticed in foamy plaque macrophages expressing “triggering receptor expressed on myeloid cells-2” (TREM2hi) evidenced by single-cell RNA, however not in neutrophils. This confirmed enhanced fibrotic signaling by PHD2cko macrophages to fibroblasts, in vitro in addition to in vivo.

Conclusion: Myeloid PHD2cko and PHD3ko enhanced atherosclerotic plaque progress and macrophage apoptosis, whereas PHD2cko macrophages additional activated collagen secretion by fibroblasts in vitro, possible through paracrine SPP1 signaling by means of TREM2hi macrophages.

Translational outlook: This research exhibits that myeloid PHD isoforms PHD2 and PHD3 worsen plaque traits and phenotype, corresponding to plaque measurement, macrophage accumulation, apoptosis, and collagen accumulation in mice. We present each direct results on macrophages and paracrine results of macrophage PHD2 loss on vessel wall fibroblast populations. Broad spectrum-PHD inhibitors, e.g. Roxadustat, are presently being prescribed to power kidney illness sufferers, who’re already in danger for heart problems. When contemplating this research and the pro-fibrotic and pro-apoptotic results we report, broad PHD inhibition might due to this fact be sub-optimal and extra focused PHD inhibition of PHD1 must be thought of.

The results of various temperatures of post-exercise protein-containing drink on gastric motility and power consumption in wholesome younger males 

The current research examined the consequences of various temperatures of protein-containing drink after train on subsequent gastric motility and power consumption in wholesome younger males. Twelve wholesome younger males accomplished three, one-day trials in a random order. In all trials, the topics ran on a treadmill for 30 min at 80% of most coronary heart fee. In train + chilly drink (2 °C) and train + sizzling drink (60 °C) trials, the topics consumed 300 mL of protein-containing drink (0.34 MJ) at 2 °C or 60 °C over a 5-min interval after train. Within the train (i.e., no preload) trial, the topics sat on a chair for five min after train. Then, the topics sat on a chair for 30 min to measure their gastric motility with an ultrasound imaging system in all trials.

Thereafter, the topics consumed a take a look at meal till they felt comfortably full. Vitality consumption within the train + sizzling drink trial was 14 % and 15 % greater than the train (P=0.046, 95% CI: 4.010-482.538) trial and train + chilly drink (P=0.001, 95% CI: 160.089-517.111) trial, respectively. The frequency of the gastric contractions within the train + sizzling drink trial was greater than the train (P=0.023) trial and train + chilly drink (P=0.007) trial. The overall frequency of gastric contractions was positively associated to power consumption (r=0.386, P=0.022). These findings reveal that consuming protein-containing drink after train at 60 °C will increase power consumption and that this improve could also be associated to the modulation of the gastric motility.

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Growth Arrest Specific Protein 6 (GAS6) Antibody

20-abx103340
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Growth Arrest Specific Protein 6 (GAS6) Antibody

20-abx103341
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Growth Arrest Specific Protein 6 (GAS6) Antibody

20-abx103342
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Growth Arrest Specific Protein 7 (GAS7) Antibody

20-abx006749
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  • 100 ul
  • 200 ul

Growth Arrest Specific Protein 8 (GAS8) Antibody

20-abx007512
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  • 100 ul
  • 200 ul
  • 30 ul

Growth Arrest Specific Protein 2 (GAS2) Antibody

20-abx001082
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Growth Arrest Specific Protein 1 (GAS1) Antibody

20-abx014505
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx030639-400ul 400 ul
EUR 627.6

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx030639-80l 80 µl
EUR 343.2

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx032914-400ul 400 ul
EUR 627.6

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx032914-80l 80 µl
EUR 343.2

Growth Arrest Specific Protein 1 (GAS1) Antibody

abx014505-100g 100 µg
EUR 43.75

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx001082-100l 100 µl
EUR 400

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx001082-20l 20 µl
EUR 175

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx001082-50l 50 µl
EUR 275

Placenta Specific Protein 9 (PLAC9) Antibody (HRP)

abx307414-100g 100 µg
EUR 362.5

Placenta Specific Protein 9 (PLAC9) Antibody (HRP)

abx307414-20g 20 µg
EUR 162.5

Placenta Specific Protein 9 (PLAC9) Antibody (HRP)

abx307414-50g 50 µg
EUR 250

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx242118-96tests 96 tests
EUR 250

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx242119-96tests 96 tests
EUR 250

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx303935-100g 100 µg
EUR 362.5

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx303935-20g 20 µg
EUR 162.5

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx303935-50g 50 µg
EUR 250

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx130151-100l 100 µl
EUR 262.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx130151-1ml 1 ml
EUR 725

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx130151-200l 200 µl
EUR 337.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx130152-100l 100 µl
EUR 262.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx130152-1ml 1 ml
EUR 725

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx130152-200l 200 µl
EUR 337.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx129509-100l 100 µl
EUR 262.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx129509-1ml 1 ml
EUR 687.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx129509-200l 200 µl
EUR 325

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx112854-100l 100 µl
EUR 612.5

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx112855-100l 100 µl
EUR 612.5

Growth Arrest Specific Protein 8 (GAS8) Antibody

abx112856-100l 100 µl
EUR 612.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx119561-100l 100 µl
EUR 312.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx119561-20l 20 µl
EUR 43.75

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx119561-50l 50 µl
EUR 237.5

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx137421-100tests 100 tests
EUR 225

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx103339-100g 100 µg
EUR 675

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx103339-20g 20 µg
EUR 250

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx103339-50g 50 µg
EUR 312.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103340-100g 100 µg
EUR 737.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103340-20g 20 µg
EUR 262.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103340-50g 50 µg
EUR 337.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103341-100g 100 µg
EUR 675

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103341-20g 20 µg
EUR 250

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103341-50g 50 µg
EUR 312.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103342-100g 100 µg
EUR 687.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103342-20g 20 µg
EUR 262.5

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx103342-50g 50 µg
EUR 325

Growth Arrest Specific Protein 1 (GAS1) Antibody

abx233349-100g 100 µg
EUR 350

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx233350-100g 100 µg
EUR 350

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx233352-100g 100 µg
EUR 350

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx233353-100g 100 µg
EUR 350

Growth Arrest Specific Protein 8 (GAS8) Antibody

abx233354-100g 100 µg
EUR 350

Growth Arrest Specific Protein 8 (GAS8) Antibody

abx241650-96tests 96 tests
EUR 250

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx030639-400l 400 µl
EUR 518.75

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx032914-400l 400 µl
EUR 518.75

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx124278-100l 100 µl
EUR 175

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx124278-1ml 1 ml
EUR 400

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx124278-200l 200 µl
EUR 275

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx146092-1096tests 10 × 96 tests Ask for price

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx146092-596tests 5 × 96 tests Ask for price

Growth Arrest Specific Protein 7 (GAS7) Antibody

abx146092-96tests 96 tests
EUR 337.5

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx211569-100l 100 µl
EUR 350

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx211569-50l 50 µl
EUR 250

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx211570-100l 100 µl
EUR 350

Growth Arrest Specific Protein 2 (GAS2) Antibody

abx211570-50l 50 µl
EUR 250

Growth Arrest Specific Protein 1 (GAS1) Antibody

abx212066-100l 100 µl
EUR 350

Growth Arrest Specific Protein 1 (GAS1) Antibody

abx212066-50l 50 µl
EUR 250

Growth Arrest Specific Protein 6 (GAS6) Antibody

abx172674-1ml 1 ml
EUR 712.5

Growth Arrest Specific Protein 8 (GAS8) Antibody

abx213853-100l 100 µl
EUR 250

Growth Arrest Specific Protein 1 (GAS1) Antibody

abx325561-100g 100 µg
EUR 250

Growth Arrest Specific Protein 1 (GAS1) Antibody

abx325561-50g 50 µg
EUR 187.5

Induction of protecting immune responses in opposition to a deadly Zika virus problem post-vaccination with a twin serotype of recombinant vesicular stomatitis virus carrying the genetically modified Zika virus E protein gene

The event of a vaccine to forestall Zika virus (ZIKV) an infection has been one of many priorities in infectious illness analysis lately. There have been quite a few makes an attempt to develop an efficient vaccine in opposition to ZIKV. It’s crucial to decide on the most secure and the best ZIKV vaccine from all candidate vaccines to manage this an infection globally. We’ve employed a twin serotype of prime-boost recombinant vesicular stomatitis virus (VSV) vaccine technique, to develop a ZIKV vaccine candidate, utilizing a kind 1 IFN-receptor knock-out (Ifnar -/-) mouse mannequin for problem research.

Prime vaccination with an attenuated recombinant VSV Indiana serotype (rVSVInd) carrying a genetically modified ZIKV envelope (E) protein gene adopted by enhance vaccination with attenuated recombinant VSV New Jersey serotype (rVSVNJ) carrying the identical E gene induced sturdy adaptive immune responses. Particularly, rVSV carrying the ZIKV E gene with the honeybee melittin sign peptide (msp) on the N terminus and VSV G protein transmembrane area and cytoplasmic tail (Gtc) on the C terminus of the E gene induced robust protecting immune responses. This vaccine routine induced extremely potent neutralizing antibodies and T cell responses within the absence of an adjuvant and guarded Ifnar -/- mice from a deadly dose of the ZIKV problem.

Chilly-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β manufacturing 

Background: Gout is an autoinflammatory illness pushed by interleukin-1 (IL-1) induction in response to uric acid crystals. IL-1β manufacturing relies on inflammasome activation, which requires a priming sign, adopted by an activating sign. The cold-inducible RNA-binding protein (CIRP) has been not too long ago recognized as a damage-associated molecular sample (DAMP). On this research, we evaluated the roles of CIRP in monosodium urate (MSU)-mediated IL-1β secretion utilizing human neutrophils. 

Strategies: Human neutrophils had been stimulated by MSU within the presence or absence of CIRP priming to find out NLRP3 inflammasome activation and subsequent caspase-1 activation and IL-1β manufacturing. Mobile supernatants had been analyzed by enzyme-linked immunosorbent assay (ELISA) to find out the presence of IL-1β or caspase-1 (p20). The mobile supernatants and lysates had been additionally analyzed by immunoblotting utilizing anti-cleaved IL-1β or anti-cleaved caspase-1 antibodies.

Outcomes: Neither CIRP nor MSU stimulation alone induced ample IL-1β secretion from neutrophils. Nevertheless, MSU stimulation induced IL-1β secretion from CIRP-primed neutrophils in a dose-dependent method. This MSU-induced IL-1β secretion from CIRP-primed neutrophils was accompanied by the induction of cleaved IL-1β (p17), which was inhibited by the pretreatment of MCC950, a selected inhibitor for NLRP3. Moreover, cleaved caspase-1 was induced within the mobile lysates of CIRP/MSU-treated neutrophils. Moreover, CIRP stimulation induced the protein expression of pro-IL-1β in neutrophils. 

Conclusions: Our knowledge point out that CIRP, an endogenous stress molecule, triggers uric acid-induced mature IL-1β induction as a priming stimulus for NLRP3 inflammasome in human neutrophils. We suggest that CIRP acts as an necessary proinflammatory stimulant that primes and prompts inflammasome and pro-IL-1β processing in response to uric acid in innate immune cells.

HDAC-9, Active Human Recombinant Protein

GWB-EAC877 10ug Ask for price

HDAC-5, Active Human Recombinant Protein

GWB-C87EF0 10ug Ask for price

HDAC-8, Active Human Recombinant Protein

GWB-C3AA2A 50ug Ask for price

HDAC-10 (GST), Active Human Recombinant Protein

GWB-9B0730 50ug Ask for price

LKB1/MO25/STRAD Active Human Recombinant Protein Complex

GWB-5E5330 20ug Ask for price

HDAC-6, GST-tag, Active Human Recombinant Protein

GWB-817DC6 50ug Ask for price

Recombinant Human SIN3-HDAC complex-associated factor (SINHCAF) (Active)

CSB-EP882059HUe0 8756 mg Ask for price

HDAC-6, FLAG-tag, Active Human Recombinant Protein

GWB-PS1E5B 50ug Ask for price

HDAC-5 full length, Active Human Recombinant Protein

GWB-74FD17 5ug Ask for price

HDAC-2, His-tag, Active Human Recombinant Protein, His Tag

GWB-A9AC3B 50ug Ask for price

HDAC-2, FLAG-tag, Active Human Recombinant Protein, FLAG Tag

GWB-767A33 50ug Ask for price

HDAC3/NcoR2 Complex, His-tag

50003 50 µg
EUR 485
Description: Complex of human HDAC3 , GenBank Accession No. NM_003883, full length with C-terminal His-tag, MW= 49.7 kDa, and human NCOR2 , a.a. 395- 489, GenBank Accession No. NM_006312, N-terminal GST-tag, MW= 37.6 kDa, co-expressed in baculovirus expression system.

Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) (Active)

CSB-YP013246HU 10277 mg Ask for price

Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) (Active)

RPC24799-100ug 100ug
EUR 465.3

Recombinant Human Lymphocyte antigen 6 complex locus protein G6d (LY6G6D) (Active)

RPC24799-20ug 20ug
EUR 288.8

HDAC10 (FLAG) Active Human Recombinant Protein

GWB-21102D 50ug Ask for price

Recombinant Human Complement C5a Protein (Active)

PKSH031511-50ug 50ug
EUR 486
Description: Human

Recombinant Rat Lymphocyte antigen 6 complex locus protein G6d (Ly6g6d) (Active)

CSB-YP750592RA 11451 mg Ask for price

Recombinant Mouse Lymphocyte antigen 6 complex locus protein G6d (Ly6g6d) (Active)

CSB-YP4973MO 11450 mg Ask for price

Active Recombinant Human Complement factor D/CFD Protein

RP01367 20μg
EUR 260

Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein(AIMP1) (Active)

AP73257 1mg
EUR 5177

Active Recombinant Human Complement C1r subcomponent Protein

RP00142 5 μg
EUR 42.25

Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein (AIMP1), partial (Active)

CSB-AP002281HU 8535 mg Ask for price

Recombinant Human C2/Complement Component 2 Protein (His Tag)(Active)

PKSH031828-20ug 20ug
EUR 508
Description: Human

Actin Related Protein 2/3 Complex, Subunit 3 Human Recombinant

rAP-2720 Inquiry Ask for price

Recombinant Human Proteasome activator complex subunit 3 (PSME3)

CSB-EP018918HU 10970 mg Ask for price

pf-HDAC-1, Active Malarial Recombinant Protein

GWB-403A1F 20ug Ask for price

Akt2 active, Active Human Recombinant Protein

GWB-A1590A 10ug Ask for price

ARPC3 Actin Related Protein 2/3 Complex, Subunit 3 Human Recombinant Protein

PROTO15145 Regular: 20ug
EUR 380.4
Description: ARPC3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-178 a.a) and having a molecular mass of 22.9kDa. ARPC3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Actin Related Protein 2/3 Complex, Subunit 5 Human (Recombinant)

22061137-1 5 µg
EUR 137.27

Actin Related Protein 2/3 Complex, Subunit 2 Human Recombinant

rAP-2721 Inquiry Ask for price

Actin Related Protein 2/3 Complex, Subunit 5 Human Recombinant

rAP-2722 Inquiry Ask for price

Sirtuin 3, Active Human Recombinant Protein

GWB-9B6EDF 100ug Ask for price

Recombinant Human Actin Related Protein 2/3 Complex, Subunit 5

7-04402 5µg Ask for price

Recombinant Human Actin Related Protein 2/3 Complex, Subunit 5

7-04403 20µg Ask for price

Recombinant Human Actin Related Protein 2/3 Complex, Subunit 5

7-04404 1mg Ask for price

Recombinant Human Proteasome activator complex subunit 3(PSME3),partial

AP72222 1mg
EUR 1978

Recombinant Human Proteasome activator complex subunit 3 (PSME3), partial

CSB-EP018918HU1 1995 mg Ask for price

Recombinant Human Proteasome activator complex subunit 3 (PSME3), partial

CSB-EP018918HU1c0 10966 mg Ask for price

ARPC2 Actin Related Protein 2/3 Complex, Subunit 2 Human Recombinant Protein

PROTO15144 Regular: 10ug
EUR 380.4
Description: ARPC2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 323 amino acids (1-300a.a) and having a molecular mass of 36.7kDa. ARPC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

ARPC5 Actin Related Protein 2/3 Complex, Subunit 5 Human Recombinant Protein

PROTO15511 Regular: 20ug
EUR 380.4
Description: ARPC5 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 171 amino acids (1-151 a.a.) and having a molecular mass of 18.4kDa. ;The ARPC5 is purified by proprietary chromatographic techniques.

Assembly Protein Complex 3 Human (Recombinant)

22061133-1 2 µg
EUR 137.27

Human CellExp? HDAC11, Human Recombinant, Active

P1267-50 each
EUR 535.2

Recombinant Human COMP Protein (His Tag)(Active)

PKSH031804-100ug 100ug
EUR 732
Description: Human

Human CellExp? HDAC6, Human Recombinant, Active

P1265-50 each
EUR 535.2

Human CellExp? HDAC8, Human Recombinant, Active

P1266-50 each
EUR 535.2

PRL-3(2-173), Active Human Recombinant Protein

GWB-PSF243 50ug Ask for price

Recombinant Human Assembly Protein Complex 3

7-04360 2µg Ask for price

Recombinant Human Assembly Protein Complex 3

7-04361 10µg Ask for price

Recombinant Human Assembly Protein Complex 3

7-04362 1mg Ask for price

Recombinant Human Proteasome activator complex subunit 2 (PSME2)

CSB-RP011344h 5086 mg Ask for price

Recombinant Human Proteasome activator complex subunit 2(PSME2)

AP71700 1mg
EUR 1978

Recombinant Human Proteasome activator complex subunit 1(PSME1)

AP76873 1mg
EUR 1978

Recombinant Human Proteasome activator complex subunit 1 (PSME1)

CSB-EP018915HU 1994 mg Ask for price

FMS, Active Human Recombinant Protein

GWB-149EA7 10ug Ask for price

CSK, Active Human Recombinant Protein

GWB-175A88 10ug Ask for price

Ret, Active Human Recombinant Protein

GWB-1E9110 10ug Ask for price

Bas, Active Human Recombinant Protein

GWB-PS58BD 20ug Ask for price

FES, Active Human Recombinant Protein

GWB-PS9783 10ug Ask for price

ULK, Active Human Recombinant Protein

GWB-A70E76 10ug Ask for price

GFP, Active Human Recombinant Protein

GWB-AC433C 200ug Ask for price

BTK, Active Human Recombinant Protein

GWB-6B7FE7 10ug Ask for price

Axl, Active Human Recombinant Protein

GWB-F65D38 10ug Ask for price

FAK, Active Human Recombinant Protein

GWB-B1A620 10ug Ask for price

ITK, Active Human Recombinant Protein

GWB-E13809 10ug Ask for price

ITK, Active Human Recombinant Protein

GWB-EFCEEA 10ug Ask for price

FAP, Active Human Recombinant Protein

GWB-C764BE 10ug Ask for price

LCK, Active Human Recombinant Protein

GWB-CBBFF1 10ug Ask for price

ITK, Active Human Recombinant Protein

GWB-BE69DC 10ug Ask for price

SNAPC1 Small Nuclear RNA Activating Complex, Polypeptide 1 Human Recombinant Protein

PROTQ16533 Regular: 20ug
EUR 380.4
Description: SNAPC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 391 amino acids (1-368 a.a) and having a molecular mass of 45.4kDa.;SNAPC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

ASCC1 Activating Signal Cointegrator 1 Complex Subunit 1 Human Recombinant Protein

PROTQ8N9N2 Regular: 10ug
EUR 380.4
Description: ASCC1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 380 amino acids (1-357) and having a molecular mass of 43.6 kDa.;ASCC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant Human Actin-related protein 2/3 complex subunit 3 (ARPC3), partial

CSB-RP033244h 5146 mg Ask for price

Recombinant Human Actin-related protein 2/3 complex subunit 3(ARPC3),partial

AP71812 1mg
EUR 1978

Active Recombinant Human IL-3 Protein

RP01362 500μg
EUR 52

DDR2 Active Human Recombinant Protein

GWB-370F00 0.01 mg Ask for price

TRKA, Active Human Recombinant Protein

GWB-43AF13 10ug Ask for price

p85a, Active Human Recombinant Protein

GWB-48E60C 100ug Ask for price

PLK1, Active Human Recombinant Protein

GWB-55E483 10ug Ask for price

NEK2, Active Human Recombinant Protein

GWB-571315 10ug Ask for price

aRAF, Active Human Recombinant Protein

GWB-5D1440 10ug Ask for price

DPP8, Active Human Recombinant Protein

GWB-5D9292 10ug Ask for price

MKK6 Active Human Recombinant Protein

GWB-6247F2 20ug Ask for price

WWP1, Active Human Recombinant Protein

GWB-64C08F 20ug Ask for price

DPP9, Active Human Recombinant Protein

GWB-662992 10ug Ask for price

DPP7, Active Human Recombinant Protein

GWB-66D491 10ug Ask for price

Flt3, Active Human Recombinant Protein

GWB-2DC31A 10ug Ask for price

TRKC, Active Human Recombinant Protein

GWB-2E1DAB 10ug Ask for price

Aha1, Active Human Recombinant Protein

GWB-331CAB 200ug Ask for price

Tie2, Active Human Recombinant Protein

GWB-341504 10ug Ask for price

Tyk2 Active Human Recombinant Protein

GWB-35FD7B 10ug Ask for price

PLK2, Active Human Recombinant Protein

GWB-16CD9F 10ug Ask for price

MDM2 Active Human Recombinant Protein

GWB-1EA32E 20ug Ask for price

Jak1 Active Human Recombinant Protein

GWB-PS3ABB 10ug Ask for price

NEK7, Active Human Recombinant Protein

GWB-PS7203 10ug Ask for price

USP7, Active Human Recombinant Protein

GWB-PS99CD 100ug Ask for price

NEK9, Active Human Recombinant Protein

GWB-PSA505 10ug Ask for price

TDP2, Active Human Recombinant Protein

GWB-PSAAD3 10ug Ask for price

PrCP, Active Human Recombinant Protein

GWB-PSC500 10ug Ask for price

cMet, Active Human Recombinant Protein

GWB-PSD799 10ug Ask for price

PKM1, Active Human Recombinant Protein

GWB-PSE52C 20ug Ask for price

cKit, Active Human Recombinant Protein

GWB-PSF7CE 10ug Ask for price

PYK2, Active Human Recombinant Protein

GWB-87F170 10ug Ask for price

CHK2, Active Human Recombinant Protein

GWB-8B3EF8 10ug Ask for price

Rheb, Active Human Recombinant Protein

GWB-A769CA 100ug Ask for price

Akt3, Active Human Recombinant Protein

GWB-676CAF 10ug Ask for price

MUSK, Active Human Recombinant Protein

GWB-6FDFEA 10ug Ask for price

EGFR, Active Human Recombinant Protein

GWB-767301 10ug Ask for price

PDK1, Active Human Recombinant Protein

GWB-7E6CB9 10ug Ask for price

Her4, Active Human Recombinant Protein

GWB-B2354A 10ug Ask for price

TRKB, Active Human Recombinant Protein

GWB-B34C75 10ug Ask for price

DPP3, Active Human Recombinant Protein

GWB-BB089E 10ug Ask for price

Akt1,Active Human Recombinant Protein

GWB-BB3CA2 10ug Ask for price

XIAP, Active Human Recombinant Protein

GWB-E21113 20ug Ask for price

AHCY, Active Human Recombinant Protein

GWB-CEAD99 50ug Ask for price

ACK1, Active Human Recombinant Protein

GWB-D2EC8D 10ug Ask for price

ROS1 Active Human Recombinant Protein

GWB-D47510 10ug Ask for price

NEK6, Active Human Recombinant Protein

GWB-D5655E 10ug Ask for price

DPP4, Active Human Recombinant Protein

GWB-C138A0 10ug Ask for price

cRAF, Active Human Recombinant Protein

GWB-C565DD 10ug Ask for price

MTAP, Active Human Recombinant Protein

GWB-C6140F 50ug Ask for price

Flt1, Active Human Recombinant Protein

GWB-C71D7F 10ug Ask for price

Her2, Active Human Recombinant Protein

GWB-BDFB0E 10ug Ask for price

Jak3, Active Human Recombinant Protein

GWB-BE5317 10ug Ask for price

PLK3, Active Human Recombinant Protein

GWB-BFCE77 10ug Ask for price

Active Recombinant Human MMP-3 Protein

RP00220 10 μg
EUR 113.75

Active Recombinant Human MMP-3 Protein

RP00220LQ 10 μg
EUR 113.75

Recombinant Human MMP-3 Protein (Active)

PKSH031588-20ug 20ug
EUR 486
Description: Human

ZAP70, Active Human Recombinant Protein

GWB-3C3FB6 10ug Ask for price

PDE3B, Active Human Recombinant Protein

GWB-495C2E 10ug Ask for price

PDE1B, Active Human Recombinant Protein

GWB-50CAF7 10ug Ask for price

DYRK2 Active Human Recombinant Protein

GWB-63A6A5 10ug Ask for price

PDE7A, Active Human Recombinant Protein

GWB-2500BE 10ug Ask for price

BRSK2, Active Human Recombinant Protein

GWB-267372 10ug Ask for price

ALAS2, Active Human Recombinant Protein

GWB-10D327 100ug Ask for price

PDE6C, Active Human Recombinant Protein

GWB-1CE561 10ug Ask for price

PTPmu, Active Human Recombinant Protein

GWB-PS0EEC 20ug Ask for price

MEKK2, Active Human Recombinant Protein

GWB-PS4378 10ug Ask for price

FGFR4, Active Human Recombinant Protein

GWB-PS501A 10ug Ask for price

RPTPg, Active Human Recombinant Protein

GWB-PS67C2 20ug Ask for price

RNF20 Active Human Recombinant Protein

GWB-PSA6BC 20ug Ask for price

UBE3A Active Human Recombinant Protein

GWB-PSF951 20ug Ask for price

UCHL3 Active Human Recombinant Protein

GWB-819E99 100ug Ask for price

PDE1C, Active Human Recombinant Protein

GWB-886086 10ug Ask for price

PDE3A, Active Human Recombinant Protein

GWB-AF80BD 10ug Ask for price

VPS34 Active Human Recombinant Protein

GWB-7FA3C0 20ug Ask for price

EphB2, Active Human Recombinant Protein

GWB-6A2C5D 10ug Ask for price

STK33 Active Human Recombinant Protein

GWB-6A33CB 10ug Ask for price

EphB4, Active Human Recombinant Protein

GWB-6ABD60 10ug Ask for price

Hsp40, Active Human Recombinant Protein

GWB-71D83F 100ug Ask for price

NEDD4, Active Human Recombinant Protein

GWB-79E152 20ug Ask for price

USP14 Active Human Recombinant Protein

GWB-FADC72 50ug Ask for price

IRAK4, Active Human Recombinant Protein

GWB-B993EE 10ug Ask for price

PDE1A, Active Human Recombinant Protein

GWB-E0AF30 10ug Ask for price

USP10 Active Human Recombinant Protein

GWB-D66F05 50ug Ask for price

FGFR2, Active Human Recombinant Protein

GWB-D9F2A2 10ug Ask for price

EphA2, Active Human Recombinant Protein

GWB-DC8558 10ug Ask for price

DAPK1 Active Human Recombinant Protein

GWB-C2E2A4 10ug Ask for price

PDE7B, Active Human Recombinant Protein

GWB-C35AC2 10ug Ask for price

PDE4B2, Active Human Recombinant Protein

GWB-3ED046 5ug Ask for price

PDE4D3, Active Human Recombinant Protein

GWB-48E7AE 5ug Ask for price

VEGFR3, Active Human Recombinant Protein

GWB-52D140 10ug Ask for price

p70S6K, Active Human Recombinant Protein

GWB-531A58 20ug Ask for price

SMURF2, Active Human Recombinant Protein

GWB-5581F8 20ug Ask for price

PDE8A1, Active Human Recombinant Protein

GWB-60E572 10ug Ask for price

PDE4D2, Active Human Recombinant Protein

GWB-63994F 0.005 mg Ask for price

ALOX15 Active Human Recombinant Protein

GWB-6672E3 20ug Ask for price

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